Macular Hole Surgery with Internal Limiting Membrane Peeling Facilitated by Membrane-Blue® versus Membrane-Blue-Dual®: A Retrospective Comparative Study

Background. This study aims to compare the outcome of macular hole (MH) surgery with internal limitingmembrane (ILM) peeling facilitated by two different vital dyes. Methods. This was a retrospective chart review. The group designated "group-MB" underwent pars plana vitrectomy with ILM peeling facilitated by Membrane-Blue (MB), whereas in "group-MBD," the vital dye used was Membrane-Blue-Dual (MBD). Results. Seventy-four eyes comprised the study population: 53 in group-MB and 21 in group-MBD. There was no difference in the rate of macular hole closure in group-MB or group-MBD: 71.2% closed MHs compared to 66.7%, respectively (P = 0.7). Postoperative visual improvement was of a highermagnitude in the MBD group compared to the MB group: -0.34 +/- 0.81 logMAR versus 0.01 +/- 0.06 logMAR, respectively (P = 0.003). Conclusions. In this study, MBD led to better visual results that may be related to better staining characteristics or lesser toxicity compared to MB.