Facile synthesis of novel 2-hydroxytetrazole derivatives via selective N-2 oxidation.

被引：15

作者：

Giles, RG ^{[1
]}

Lewis, NJ ^{[1
]}

Oxley, PW ^{[1
]}

Quick, JK ^{[1
]}

机构：

[1] SmithKline Beecham Pharmaceut, Dept Synthet Chem, Tonbridge TN11 9AN, Kent, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 33期

关键词：

D O I：

10.1016/S0040-4039(99)01269-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly selective oxidation of the sodium salt of ethyl tetrazole-5-carboxylate is reported which produces a novel class of hydroxytetrazole derivative which can then be converted to 2-hydroxytetrazole, A novel preparation of 1-hydroxytetrazole is also reported. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：6093 / 6094

页数：2

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