Facile synthesis of novel 2-hydroxytetrazole derivatives via selective N-2 oxidation.

被引：16

作者：

Giles, RG ^{[1
]}

Lewis, NJ ^{[1
]}

Oxley, PW ^{[1
]}

Quick, JK ^{[1
]}

机构：

[1] SmithKline Beecham Pharmaceut, Dept Synthet Chem, Tonbridge TN11 9AN, Kent, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 33期

关键词：

D O I：

10.1016/S0040-4039(99)01269-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly selective oxidation of the sodium salt of ethyl tetrazole-5-carboxylate is reported which produces a novel class of hydroxytetrazole derivative which can then be converted to 2-hydroxytetrazole, A novel preparation of 1-hydroxytetrazole is also reported. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：6093 / 6094

页数：2

共 10 条

[1] PREPARATION OF N-HYDROXYAZOLES BY OXIDATION OF AZOLES [J].

BEGTRUP, M ;

VEDSO, P .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1995, (03) :243-247

[2]

CHURAKOV AM, 1988, KHIM GETEROTSIKL+, P1666

[3]

DZIKLINSKA H, 1989, B SOC CHIM BELG, V98, P277

[4]

LUKYANOV OA, 1987, IAN SSSR KH, P2540

[5]

LUKYANOV OA, 1989, IAN SSSR KH, P1619

[6]

LUKYANOV OA, 1987, IAN SSSR KH, P2376

[7]

Maffei S., 1956, ANN CHIM-ROME, V46, P812

[8]

PALLAZZO FC, 1913, GAZZ CHIM ITAL, V43, P69

[9]

PALLAZZO FC, 1910, ATTI ACCAD NAZ LINCE, V19, P228

[10] Novel acylation catalysts in peptide synthesis:: derivatives of N-hydroxytriazoles and N-hydroxytetrazoles [J].

Spetzler, JC ;

Meldal, M ;

Felding, J ;

Vedso, P ;

Begtrup, M .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1998, (10) :1727-1732

← 1 →