Therapeutic and Diagnostic Challenges in Myasthenia Gravis

被引：6

作者：

Thy Nguyen ^{[1
]}

Phan, Cecile L. ^{[2
]}

Supsupin, Emilio, Jr. ^{[3
]}

Sheikh, Kazim ^{[4
]}

机构：

[1] Univ Texas Hlth Sci Ctr Houston, Dept Neurol, McGovern Med Sch, 6431 Fannin St,MSE R 462, Houston, TX 77030 USA

[2] 7-125 Clin Sci Bldg, Edmonton, AB T6G 2R7, Canada

[3] Dept Diagnost & Intervent Imaging, 6431 Fannin St 2-103 MSMB, Houston, TX 77030 USA

[4] Univ Texas Hlth Sci Ctr Houston, Dept Neurol, McGovern Med Sch, 6431 Fannin St,MSE R454, Houston, TX 77030 USA

来源：

NEUROLOGIC CLINICS | 2020年 / 38卷 / 03期

关键词：

Neuromuscular junction disorder; Myasthenia gravis; Ptosis; Weakness; CLINICAL CHARACTERISTICS; MUSK; PREGNANCY; RITUXIMAB; EPIDEMIOLOGY; BIRTH; RISK;

D O I：

10.1016/j.ncl.2020.03.005

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

“Myasthenia gravis (MG) is the most common autoimmune neuromuscular disorder. This article highlights several cases that the practicing neurologist may encounter in the treatment of MG. Diagnostic uncertainty continues to be an issue in patients who are seronegative to the 2 most common antibodies, acetylcholine receptor and muscle-specific tyrosine kinase (MuSK). Specific populations of patients with MG including MuSK MG, thymomatous MG, refractory MG, and pregnant women also require special consideration. This article reviews specific cases and an update on current management.” © 2020

引用

页码：577 / 590

页数：14

共 30 条

[1] Course and treatment of myasthenia gravis during pregnancy
Batocchi, AP
Majolini, L
Evoli, A
Lino, MM
Minisci, C
Tonali, P
[J]. NEUROLOGY, 1999, 52 (03) : 447 - 452
[2] Rituximab in refractory myasthenia gravis: Extended prospective study results
Beecher, Grayson
Anderson, Dustin
Siddiqi, Zaeem A.
[J]. MUSCLE & NERVE, 2018, 58 (03) : 452 - 455
[3] Myasthenia gravis: a clinical-immunological update
Binks, Sophie
Vincent, Angela
Palace, Jacqueline
[J]. JOURNAL OF NEUROLOGY, 2016, 263 (04) : 826 - 834
[4] Myasthenia gravis and tumours of the thymic region - Report of a case in which the tumor was removed
Blalock, A
Mason, MF
Morgan, HJ
Riven, SS
[J]. ANNALS OF SURGERY, 1939, 110 : 544 - 561
[5] THE THYMUS IN MYASTHENIA GRAVIS: SITE OF "INNATE AUTOIMMUNITY"?
Cavalcante, Paola
Le Panse, Rozen
Berrih-Aknin, Sonia
Maggi, Lorenzo
Antozzi, Carlo
Baggi, Fulvio
Bernasconi, Pia
Mantegazza, Renato
[J]. MUSCLE & NERVE, 2011, 44 (04) : 467 - 484
[6] Thymectomy may not be associated with clinical improvement in MuSK myasthenia gravis
Clifford, Katherine M.
Hobson-Webb, Lisa D.
Benatar, Michael
Burns, Ted M.
Barnett, Carolina
Silvestri, Nicholas J.
Howard, James F.
Visser, Amy
Crum, Brian A.
Nowak, Richard
Beekman, Rachel
Kumar, Aditya
Ruzhansky, Katherine
Chen, I-Hweii Amy
Pulley, Michael T.
Laboy, Shannon M.
Fellman, Melissa A.
Howard, Diantha B.
Kolb, Noah A.
Greene, Shane M.
Pasnoor, Mamatha
Dimachkie, Mazen M.
Barohn, Richard J.
Hehir, Michael K.
[J]. MUSCLE & NERVE, 2019, 59 (04) : 404 - 410
[7] Clinical follow-up of pregnancy in myasthenia gravis patients
Ducci, Renata D.
Lorenzoni, Paulo J.
Kay, Claudia S. K.
Werneck, Lineu C.
Scola, Rosana H.
[J]. NEUROMUSCULAR DISORDERS, 2017, 27 (04) : 352 - 357
[8] ANTI-MuSK ANTIBODY MYASTHENIA GRAVIS: CLINICAL FINDINGS AND RESPONSE TO TREATMENT IN TWO LARGE COHORTS
Guptill, Jeffrey T.
Sanders, Donald B.
Evoli, Amelia
[J]. MUSCLE & NERVE, 2011, 44 (01) : 36 - 40
[9] Outcomes After Transcervical Thymectomy for Ocular Myasthenia Gravis: A Retrospective Cohort Study With Inverse Probability Weighting
Hamedani, Ali G.
Pistilli, Maxwell
Singhal, Sunil
Shindler, Kenneth S.
Avery, Robert A.
Tamhankar, Madhura A.
Liu, Grant T.
[J]. JOURNAL OF NEURO-OPHTHALMOLOGY, 2020, 40 (01) : 8 - 14
[10] An Update: Myasthenia Gravis and Pregnancy
Hamel, Johanna
Ciafaloni, Emma
[J]. NEUROLOGIC CLINICS, 2018, 36 (02) : 355 - +

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