Botulinum toxin therapy of writer's cramp

被引：19

作者：

Das, CP ^{[1
]}

Dressler, D

Hallett, M

机构：

[1] Postgrad Inst Med Educ & Res, Dept Neurol, Chandigarh 160012, India

[2] Univ Rostock, Dept Neurol, D-2500 Rostock, Germany

[3] NINDS, Human Motor Control Sect, NIH, Bethesda, MD 20892 USA

来源：

EUROPEAN JOURNAL OF NEUROLOGY | 2006年 / 13卷

关键词：

botulinum toxin; dystonia; writer's cramp;

D O I：

10.1111/j.1468-1331.2006.01446.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The pathophysiology and management of writer's cramp is one of the most challenging amongst the various forms of focal dystonias. Frequently, the dystonic postures are confounded by compensatory muscle activity. Correct identification of target muscles for botulinum toxin (BT) injections determines the treatment success. The dosages of different preparations vary, with 1 unit of Botox (R) roughly equalling 3.5 units of Dysport (R). Electromyographic guided injections yield better results and may also decrease the amount of toxin required. Weakness of target muscles interfering with other non-writing activities is a frequently encountered adverse effect. Studies have shown that BT is a safe long-term therapy option.

引用

页码：55 / 59

页数：5

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