Biodegradable Cell-Seeded Collagen Based Polymer Scaffolds for Wound Healing and Skin Reconstruction

被引：20

作者：

Ansari, Mojtaba ^{[1
]}

Kordestani, Soheila Salahshoor ^{[2
]}

Nazralizadeh, Sanaz ^{[2
]}

Eslami, Hossein ^{[1
]}

机构：

[1] Meybod Univ, Dept Biomed Engn, POB 89616-99557, Meybod, Yazd, Iran

[2] Amirkabir Univ Technol, Fac Biomed Engn, Tehran, Iran

来源：

JOURNAL OF MACROMOLECULAR SCIENCE PART B-PHYSICS | 2018年 / 57卷 / 02期

关键词：

Amniotic fluid-derived stem (AFS) cells; collagen-glycosaminoglycan scaffolds; extracellular matrix; wound dressings; wound healing; DRUG-DELIVERY; TISSUE; SYSTEMS;

D O I：

10.1080/00222348.2018.1435617

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

In the present study a collagen-glycosaminoglycans scaffold, following chemical modifications, was prepared as an analog of the extracellular matrix (ECM) by a freeze drying method. Appropriate tests related to its use for wound healing (evaluation of the structure by scanning electron microscopy, swelling properties, biodegradability properties, Fourier transform infrared spectroscopy and cell culture) were done on the scaffolds. Amniotic fluid-derived stem (AFS) cell seeded scaffolds were shown to be potentially useful for wound healing.

引用

页码：100 / 109

页数：10

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