Hydroxychloroquine ototoxicity in a child with idiopathic pulmonary haemosiderosis

被引：20

作者：

Coutinho, MB ^{[1
]}

Duarte, I ^{[1
]}

机构：

[1] Hosp Criancas Maria Pia, Dept Otolaryngol, P-4050111 Oporto, Portugal

来源：

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY | 2002年 / 62卷 / 01期

关键词：

ototoxicity; hydroxychloroquine; idiopathic pulmonary haemosiderosis;

D O I：

10.1016/S0165-5876(01)00592-4

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Hydroxychloroquine, a quinoline compound, rarely causes ototoxicity. According to the few reports in existence, hydroxychloroquine-induced ototoxicity occurred following prolonged therapy in adult patients with rheumatoid arthritis and lupus erythematosus. We report a case of unilateral sensorineural hearing loss in a 7-year-old girl with idiopathic pulmonary haemosiderosis, after 2 years of hydroxychloroquine treatment. Sensorineural hearing loss has previously been reported with hydroxychloroquine treatment, but this is the first report in a child and associated to idiopathic pulmonary haemosiderosis and has the characteristic of being unilateral. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：53 / 57

页数：5

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