Hydroxychloroquine ototoxicity in a child with idiopathic pulmonary haemosiderosis

被引：19
作者：
Coutinho, MB [1 ]
Duarte, I [1 ]
机构：
[1] Hosp Criancas Maria Pia, Dept Otolaryngol, P-4050111 Oporto, Portugal
来源：
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY | 2002年 / 62卷 / 01期
关键词：
ototoxicity; hydroxychloroquine; idiopathic pulmonary haemosiderosis;
D O I：
10.1016/S0165-5876(01)00592-4
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Hydroxychloroquine, a quinoline compound, rarely causes ototoxicity. According to the few reports in existence, hydroxychloroquine-induced ototoxicity occurred following prolonged therapy in adult patients with rheumatoid arthritis and lupus erythematosus. We report a case of unilateral sensorineural hearing loss in a 7-year-old girl with idiopathic pulmonary haemosiderosis, after 2 years of hydroxychloroquine treatment. Sensorineural hearing loss has previously been reported with hydroxychloroquine treatment, but this is the first report in a child and associated to idiopathic pulmonary haemosiderosis and has the characteristic of being unilateral. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：53 / 57
页数：5
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