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Stem cells for reprogramming: could hUMSCs be a better choice?
被引:11
|作者:
Duya, Paulina
[1
]
Bian, Yuhong
[1
]
Chu, Xiaoqian
[1
]
Zhang, Yanjun
[1
]
机构:
[1] Tianjin Univ Tradit Chinese Med, Tianjin, Peoples R China
基金:
中国国家自然科学基金;
关键词:
Human umbilical cord mesenchymal stem cells;
Embryonic stem cells;
Pluripotency;
Reprogramming;
HUMAN UMBILICAL-CORD;
MESENCHYMAL PROGENITOR CELLS;
BONE-MARROW;
AUTOIMMUNE-DISEASE;
STROMAL CELLS;
SELF-RENEWAL;
IN-VITRO;
BLOOD;
DIFFERENTIATION;
TRANSPLANTATION;
D O I:
10.1007/s10616-012-9489-3
中图分类号:
Q81 [生物工程学(生物技术)];
Q93 [微生物学];
学科分类号:
071005 ;
0836 ;
090102 ;
100705 ;
摘要:
Human umbilical cord mesenchymal stem cells (hUMSC) are primitive multipotent cells capable of differentiating into cells of different lineages. They can be an alternative source of pluripotent cells since they are ethically and regulatory approved, are easily obtained and have low immunogenicity compared to embryonic stem cells which are dogged with numerous controversies. hUMSC can be a great source for cell and transplantation therapy.
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页码:335 / 345
页数:11
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