Detection of Carboxyhemefibrinogen and Methemefibrinogen in a Patient with Thrombosis of a HeartMate II Ventricular Assist Device

被引:11
|
作者
Smith, M. Cristina [2 ]
Nielsen, Vance G. [1 ]
机构
[1] Univ Arizona, Coll Med, Dept Anesthesiol, Tucson, AZ 85724 USA
[2] Univ Arizona, Coll Med, Dept Surg, Tucson, AZ 85724 USA
关键词
ventricular assist device; thrombosis; carbon monoxide; thrombelastography; fibrinogen; CARBON-MONOXIDE;
D O I
10.1097/MAT.0b013e31827986e6
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Ventricular assist device (VAD) thrombosis is a devastating, potentially fatal complication suffered by patients requiring mechanical circulatory support. We present a patient with thrombosis of a HeartMate II VAD with concurrent hemolysis and increased carbon monoxide formation. Using a specialized thrombelastographic assay, we detected marked plasmatic hypercoagulability mediated in part by the formation of carboxyhemefibrinogen. ASAIO Journal 2013;59:93-95.
引用
收藏
页码:93 / 95
页数:3
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