Therapeutic plasma exchange: A technical and operational review

被引：108

作者：

Kaplan, Andre A. ^{[1
]}

机构：

[1] Univ Connecticut, Ctr Hlth, Storrs, CT 06269 USA

来源：

JOURNAL OF CLINICAL APHERESIS | 2013年 / 28卷 / 01期

关键词：

therapeutic plasma exchange; plasmapheresis; apheresis; SYSTEMIC LUPUS-ERYTHEMATOSUS; STARCH REPLACEMENT; IMMUNE GLOBULIN; HEPATITIS-C; PLASMAPHERESIS; ALBUMIN; KINETICS; VOLUME; INFECTIONS; APHERESIS;

D O I：

10.1002/jca.21257

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Therapeutic plasma exchange (TPE) is an extracorporeal blood purification technique designed for the removal of large molecular weight substances. Examples of these substances include pathogenic autoantibodies, immune complexes, cryoglobulins, myeloma light chains, endotoxin and cholesterol containing lipoproteins. The basic premise of the treatment is that removal of these substances will allow for the reversal of the pathologic processes related to their presence. This review will cover the techniques for performing TPE, the kinetics of the removal of large molecules from the plasma and the benefits and risks of the different types of replacement fluids. J. Clin. Apheresis 28:310, 2013. (c) 2013 Wiley Periodicals, Inc.

引用

页码：3 / 10

页数：8

共 66 条

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