Introduction to regenerative medicine and tissue engineering

被引:5
|
作者
Stoltz, J-F [1 ,2 ,3 ,4 ]
Decot, V. [1 ,2 ,3 ,4 ]
Huseltein, C. [1 ,2 ,4 ]
He, X. [5 ,6 ]
Zhang, L. [7 ]
Magdalou, J. [1 ,2 ,4 ]
Li, Y. P. [5 ,6 ]
Menu, P. [1 ,2 ,4 ]
Li, N. [8 ]
Wang, Y. Y. [1 ,2 ,4 ,5 ,6 ]
de Isla, N. [1 ,2 ,4 ]
Bensoussan, D. [1 ,2 ,3 ,4 ]
机构
[1] CNRS, UMR 7561, F-54500 Vandoeuvre Les Nancy, France
[2] FR CNRS UHP CHU 3209, Fac Med, F-54500 Vandoeuvre Les Nancy, France
[3] CHU Nancy, Hop Brabois, Unite Therapie Cellulaire & Tissulaire, F-54500 Vandoeuvre Les Nancy, France
[4] Univ Henri Poincare, Nancy Univ, Nancy, France
[5] Wuhan Univ, Dept Biotherapy, Coll Med, Wuhan 430072, Peoples R China
[6] Wuhan Univ, Zhongnan Univ Hosp, Wuhan 430072, Peoples R China
[7] Hop Univ Calmette, Biomed Res Ctr, Kunming, Peoples R China
[8] Anzen Univ Hosp, Beijing Inst Cardiovasc Dis, Beijing, Peoples R China
关键词
Stem cells; cell therapy; tissue engineering; biotissue; scaffold; mechanotransduction; MESENCHYMAL STEM-CELLS; HUMAN BONE-MARROW; CORD BLOOD; PROGENITOR CELLS; ENDOTHELIAL-CELLS; STROMAL CELLS; MECHANICAL STIMULATION; EXTRACELLULAR-MATRIX; GENE-EXPRESSION; ADIPOSE-TISSUE;
D O I
10.3233/BME-2012-0684
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Human tissues don't regenerate spontaneously, explaining why regenerative medicine and cell therapy represent a promising alternative treatment (autologous cells or stem cells of different origins). The principle is simple: cells are collected, expanded and introduced with or without modification into injured tissues or organs. Among middle-term therapeutic applications, cartilage defects, bone repair, cardiac insufficiency, burns, liver or bladder, neurodegenerative disorders could be considered.
引用
收藏
页码:3 / 16
页数:14
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