HLA-B☆58:01 is strongly associated with allopurinol-induced severe cutaneous adverse reactions in Han Chinese patients: a multicentre retrospective case-control clinical study

被引:36
作者
Cheng, L. [1 ,3 ]
Xiong, Y. [1 ,3 ]
Qin, C. Z. [1 ,3 ]
Zhang, W. [1 ,3 ]
Chen, X. P. [1 ,3 ]
Li, J. . [2 ]
Zhou, H. H. [1 ,3 ]
机构
[1] Cent S Univ, Xiangya Hosp, Dept Clin Pharmacol, Changsha 410008, Hunan, Peoples R China
[2] Cent S Univ, Xiangya Hosp, Dept Dermatol, Changsha 410008, Hunan, Peoples R China
[3] Cent S Univ, Hunan Key Lab Pharmacogenet, Inst Clin Pharmacol, Changsha 410078, Hunan, Peoples R China
关键词
TOXIC EPIDERMAL NECROLYSIS; STEVENS-JOHNSON-SYNDROME; HIGH PREVALENCE; HLA-B; ALLELE; DRUGS; HLA-B-ASTERISK-5801; HYPERURICEMIA; RISK;
D O I
10.1111/bjd.13688
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:555 / 558
页数:4
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