Organotin (IV) derivatives of 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (nalidixic acid): Synthesis, structural elucidation and biological activities

被引：0

作者：

Ahmed, Sajjad ^{[1
]}

Bhatti, Moazzam Hussain ^{[1
]}

Ali, Saqib ^{[1
]}

Ahmed, Fiaz ^{[1
]}

机构：

[1] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan

来源：

TURKISH JOURNAL OF CHEMISTRY | 2006年 / 30卷 / 02期

关键词：

organotin(IV) complexes; 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (nalidixic acid); spectroscopic characterization; biological activity;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Organotin carboxylates of the general formulae R2SnL2 and R3SnL, where R = CH3, n-C4H9, C6H5, CH2C6H5 and L = 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (nalidixic acid), have been prepared. These compounds were characterized by FT-IR, mass and multinuclear NMR (H-1, C-13 and Sn-119) spectroscopy. The geometry around the tin atom is compared both in solution and in solid state. These compounds were also screened for their antifungal and antibacterial activities.

引用

页码：193 / 202

页数：10

共 22 条

[1] Synthesis, characterization, and biological studies of tri- and diorganotin(IV) complexes with 2′,4′-difluoro-4-hydroxy-[1,1′]biphenyle-3-carbolic acid:: Crystal structure of [(CH3)3Sn(C13H7O3F2)] [J].