Molecular Interaction of Nanoparticles with Proteins

被引：0

作者：

Xu Zhizhen ^{[1
,2
]}

Yan Xiaomin ^{[3
]}

Zhang Jie ^{[2
,4
]}

Wang Yuqian ^{[2
]}

Tang Shichuan ^{[2
]}

Zhong Rugang ^{[1
]}

机构：

[1] Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China

[2] Beijing Key Lab Occupat Safety & Hlth, Beijing 100054, Peoples R China

[3] S China Normal Univ, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China

[4] Beijing Inst Technol, State Key Lab Explos Sci & Technol, Beijing 100081, Peoples R China

来源：

PROGRESS IN CHEMISTRY | 2013年 / 25卷 / 08期

关键词：

nanoparticles; protein; interaction; protein structure; biological effect; ULTRAFINE PARTICLES; COPOLYMER NANOPARTICLES; POLYMERIC NANOPARTICLES; SILVER NANOPARTICLES; SILICA NANOPARTICLES; COLLOIDAL STABILITY; ADSORBED PROTEINS; CARBON NANOTUBES; AMORPHOUS SILICA; PLASMA-PROTEINS;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The rapid development of nanotechnology offers wide prospects for the application of nanomaterials in different areas of industry, technology and medicine. Meanwhile, the biological effect and safety of nanoparticles have attracted worldwide attention. To ensure the healthy and sustainable development of nanotechnology,, the interaction of nanoparticles with organisms and the biological effect produced by nanoparticles can not be neglected. To understand the biological effects of nanoparticles, investigating how the nanoparticles entrance into organisms and the complicated molecular aspects of nano-bio interactions is crucial. The main routes of nanoparticles entering the organisms are introduced. The interaction of nanoparticles with protein, the influencing factors and characterization of the interaction are reviewed in detail. The effects of nano-protein interaction on the structure and function of protein and the biological impact of nanoparticles are summarized.

引用

页码：1383 / 1391

页数：9

共 73 条

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