L-Proline catalyzed efficient and convenient synthesis of substituted 2H-chromenes by three-component reaction

被引：39

作者：

Rao, L. Chandrasekhara ^{[1
]}

Meshram, H. M. ^{[1
]}

Kumar, N. Satish ^{[1
]}

Rao, N. Nageswara ^{[1
]}

Babu, N. Jagadeesh ^{[2
]}

机构：

[1] CSIR Indian Inst Chem Technol, Med Chem & Pharmacol Div, Hyderabad 500007, Andhra Pradesh, India

[2] CSIR Indian Inst Chem Technol, Lab Xray Crystallog, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 06期

关键词：

Salicylaldehyde; Pentane-2; 4-Dione; 2H-Chromens; L-Proline; SOLID-PHASE SYNTHESIS; SOLVENT-FREE SYNTHESIS; COMBINATORIAL LIBRARIES; PRIVILEGED STRUCTURES; ONE-POT; RHODODENDRON-DAURICUM; DERIVATIVES; BENZOPYRANS; ALDEHYDES; KETONES;

D O I：

10.1016/j.tetlet.2013.10.091

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient and efficient method is described for the synthesis of alkoxy substituted 2H-chromens by L-proline catalyzed reaction of salicylaldehydes with diketone in alcohol. The method is applicable for various substituted salicylaldehydes and aliphatic as well as benzylic alcohols. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：1127 / 1131

页数：5

共 51 条

[1] One-Pot Three-Component Synthesis of 4(3H)-Quinazolinones from Benzyl Halides, Isatoic Anhydride, and Primary Amines [J].