Quantitative susceptibility mapping (QSM) evaluation of infantile neuroaxonal dystrophy

被引：3

作者：

Fujiwara, Takuya ^{[1
]}

Watanabe, Yoshiyuki ^{[1
]}

Tanaka, Hisashi ^{[1
]}

Takahashi, Hiroto ^{[1
]}

Nabatame, Shin ^{[2
]}

Yi, Wang ^{[3
]}

Tomiyama, Noriyuki ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Med, Diagnost & Intervent Radiol, Suita, Osaka, Japan

[2] Osaka Univ, Grad Sch Med, Dept Pediat, Suita, Osaka, Japan

[3] Cornell Univ, Biomed Engn, Ithaca, NY USA

来源：

BJR CASE REPORTS | 2019年 / 5卷 / 02期

关键词：

NEURODEGENERATION;

D O I：

10.1259/bjrcr.20180078

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We present the first case of twins with infantile neuroaxonal dystrophy evaluating brain iron deposition using quantitative susceptibility mapping (QSM). A 6-year-old boy who was normal at birth had psychomotor regression and hypotonia from 2-years-old. Brain MRI showed low intensity areas in globus pallidus (GP) and substantia nigra (SN) on T-2* weighted imaging. QSM values of GP and SN were 0.19 and 0.29 ppm, respectively. His twin brother showed almost the same imaging findings. Follow-up MRI revealed increase of QSM value in GP and SN.

引用

页数：3

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