Intratubular Germ Cell Neoplasia of the Testis, Bilateral Testicular Cancer, and Aberrant Histologies

被引：9

作者：

Sharma, Pranav ^{[1
]}

Dhillon, Jasreman ^{[2
]}

Sexton, Wade J. ^{[1
]}

机构：

[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Genitourinary Oncol, Tampa, FL 33612 USA

[2] H Lee Moffitt Canc Ctr & Res Inst, Dept Genitourinary Anat Pathol, Tampa, FL 33612 USA

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2015年 / 42卷 / 03期

关键词：

CARCINOMA-IN-SITU; INTRAEPITHELIAL NEOPLASIA; CONTRALATERAL TESTIS; CLINICAL-OUTCOMES; HISTOPATHOLOGICAL ABNORMALITIES; MICROLITHIASIS PREDICTS; SPARING SURGERY; TUMORS; RISK; MEN;

D O I：

10.1016/j.ucl.2015.04.002

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Intratubular germ cell neoplasia (ITGCN) is a precursor lesion for testicular germ cell tumors, most of which are early stage. ITGCN is also associated with testicular cancer or ITGCN in the contralateral testis, leading to a risk of bilateral testicular malignancy. Testicular biopsy detects most cases, and orchiectomy is the treatment of choice in patients with unilateral ITGCN. Low-dose radiation therapy is recommended in patients with bilateral ITGCN or ITGCN in the solitary testis, but the long-term risks of infertility and hypogonadism need to be discussed with the patient. Rare histologies of primary testicular cancer are also discussed.

引用

页码：277 / +

页数：10

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