Ruthenium-Catalyzed Alkyne Annulations with Substituted 1H-Pyrazoles by C-H/N-H Bond Functionalizations

被引：84

作者：

Ma, Wenbo ^{[1
]}

Graczyk, Karolina ^{[1
]}

Ackermann, Lutz ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 24期

基金：

欧洲研究理事会;

关键词：

OXIDATIVE ALKENYLATION; ACTIVATION; PALLADIUM; PHENYLAZOLES; CYCLIZATION; ARYLATIONS; MECHANISM; CLEAVAGE; INDOLES; ACIDS;

D O I：

10.1021/ol303083n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cationic ruthenium(II) complexes allowed for highly efficient oxidative annulations of aryl- and alkyl-substituted alkynes by 5-aryl-1H-pyrazoles. The C-H/N-H bond functionalization strategy furthermore proved applicable to the high-yielding activation of heteroaryl as well as alkenyl C-H bonds.

引用

页码：6318 / 6321

页数：4

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