Assessment of measles incidence, measles-related complications and hospitalisations during an outbreak in a southern Italian region

被引:17
作者
degli Atti, MLC
Filia, A
Massari, M
Pizzuti, R
Nicoletti, L
D'Argenzio, A
de Campora, E
Marchi, A
Lombardo, A
Salmaso, S
机构
[1] Ist Super Sanita, Ctr Nazl Epidemiol Sorveglianza & Promoz Salute, Reparto Epidemiol Malattie Infett, I-00161 Rome, Italy
[2] Osservatorio Epidemiol Reg, Naples, Italy
[3] Ist Super Sanita, Dipartimento Malattie Infett, Reparto Malattie Virali & Vaccini Attenuati, I-00161 Rome, Italy
[4] ASL Caserta 2, Aversa, Italy
[5] Agenzia Reg Serv Sanitari, Naples, Italy
关键词
measles epidemic; surveillance; vaccination;
D O I
10.1016/j.vaccine.2005.09.031
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A large measles epidemic occurred in 2002 in Campania, a region of southern Italy with inadequate vaccination coverage. We evaluated the burden of the outbreak in children < 15 years of age using different data sources. The measles standardized incidence rate was 5757/100,000, corresponding to 63,368 estimated cases (95% CI: 59,544-67,373). Measles virus strains were identified as belonging to the D7 genotype. The estimated complication rate was 7.6%. A total of 972 measles hospitalisations were detected, giving a hospitalisation rate of 88.3/100,000. Three deaths occurred. These results show that measles can still represent a serious health threat even in industrialized Countries. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1332 / 1338
页数:7
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