Multimodal treatment of testicular cancer: chemotherapy, surgery or radiotherapy?

Background: Metastatic testicular germ cell tumors patients require histology- and stage-appropriate therapy to achieve optimal therapeutic outcomes. Objectives: This work focuses on the interdisciplinary presentation of current recommendations for the treatment of metastatic germ cell tumor patients. Materials and methods: The interdisciplinary recommendations were formulated based on the German S3 guideline and supplemented by recent literature. Results: Using a stage-specific and guideline-based treatment approach, interdisciplinary cooperation between urology, oncology, and radiotherapy is mandatory to successfully achieve a high rate of cure and, in the case of complex advanced tumors, also themost effective therapy possible. The question of optimal treatment approaches for seminoma in cSII A/B remains particularly challenging. Conclusion: Since treatment of advanced ormultiple relapsed germ cell tumor patients remains complex, patients should be referred for an online second opinion (https:// urologie.ekonsil.org).