Efficient, Solvent-Free, Multicomponent Method for Organic-Base-Catalyzed Synthesis of β-Phosphonomalonates

被引：23

作者：

Kalla, Reddi Mohan Naidu ^{[1
]}

Park, Huiju ^{[1
]}

Lee, Hye Ri ^{[1
]}

Suh, Hongsuk ^{[2
,3
]}

Kim, Il ^{[1
]}

机构：

[1] Pusan Natl Univ, Dept Polymer Sci & Engn, PLUS Ctr Adv Chem Technol BK21, Busan 609735, South Korea

[2] Pusan Natl Univ, Dept Chem, Busan 609735, South Korea

[3] Pusan Natl Univ, Chem Inst Funct Mat, Busan 609735, South Korea

来源：

ACS COMBINATORIAL SCIENCE | 2015年 / 17卷 / 11期

基金：

新加坡国家研究基金会;

关键词：

beta-phosphonomalonate; multicomponent reaction; organocatalyst; solvent-free; ONE-POT SYNTHESIS; RECYCLABLE HETEROGENEOUS CATALYST; PHOSPHA-MICHAEL ADDITION; SOLID ACID CATALYST; HIGHLY EFFICIENT; SULFONIC-ACID; HYDROXYPHOSPHONATES; GAMMA-FE2O3; DESIGN;

D O I：

10.1021/acscombsci.5b00109

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An efficient, one-pot, di-n-butylamine-catalyzed, three-component synthesis of beta-phosphonomalonates has been developed. A wide range of substrates, including aromatic and fused aromatic aldehydes, were condensed with enolizable C-H activated compounds and dialkylphosphites to give the desired products in excellent yields. This method provides an eco-friendly alternative approach to rapid construction of a diversity-oriented library of beta-phosphonomalonates.

引用

页码：691 / 697

页数：7

共 50 条

[21] MCM-41 Catalyzed Efficient Regioselective Synthesis of β-Aminoalcohol under Solvent-free Conditions
Heravi, Majid M.
Bakhtiari, Khadijeh
Alinejhad, Hamideh
Saeedi, Mina
Malakooti, Reihane
CHINESE JOURNAL OF CHEMISTRY, 2010, 28 (02) : 269 - 272
[22] An efficient solvent-free synthesis of benzoxanthenes catalyzed by BSA or o-TSA
Luo, G.
Liu, D.
Liu, C.
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, 2008, 38 (03) : 265 - 270
[23] Aluminized polyborate-catalysed green and efficient synthesis of polyhydroquinolines under solvent-free conditions
Aute, Dilip
Kshirsagar, Akshay
Uphade, Bhagwat
Gadhave, Anil
RESEARCH ON CHEMICAL INTERMEDIATES, 2020, 46 (07) : 3491 - 3508
[24] Alternative solvent-free methodologies in the synthesis of pharmaceutical drugs
Shearouse, William C.
Waddell, Daniel C.
Mack, James
CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2009, 12 (06) : 772 - 783
[25] Efficient, Solvent-Free Aminolysis of Monoesters Catalyzed by Sodium
Shen, Tao
Ouyang, Bo
Zhou, Shaodong
Qian, Chao
Chen, Xinzhi
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 39 (03) : 873 - 877
[26] An efficient synthesis of 1-amidoalkyl-2-naphthols catalyzed by zinc oxide nanoparticles under solvent-free conditions
Singh, Rajesh K.
Bala, Renu
Kumar, Sahil
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2016, 55 (03): : 381 - 386
[27] Three-component, solvent-free synthesis of Betti base catalyzed by sulfated polyborate
Manisha S. Patil
Chetan K. Khatri
Ganesh U. Chaturbhuj
Monatshefte für Chemie - Chemical Monthly, 2018, 149 : 1453 - 1457
[28] A Base and Solvent-Free Ruthenium-Catalyzed Alkylation of Amines
Celaje, Jeff Joseph A.
Zhang, Xingyue
Zhang, Forrest
Kam, Lisa
Herron, Jessica R.
Williams, Travis J.
ACS CATALYSIS, 2017, 7 (02): : 1136 - 1142
[29] Multicomponent synthesis of bioactive 1-amidoalkyl-2-naphtols under solvent-free conditions
Hajjami, M.
Ghorbani-Choghamarani, A.
Gholamian, F.
BULGARIAN CHEMICAL COMMUNICATIONS, 2015, 47 (01): : 119 - 124
[30] A stereoselective organic base-catalyzed protocol for hydroamination of alkynes under solvent-free conditions
Kozell, Vadym
Rahmani, Fariba
Piermatti, Oriana
Lanari, Daniela
Vaccaro, Luigi
MOLECULAR CATALYSIS, 2018, 455 : 188 - 191

← 1 2 3 4 5 →