Operative management of brainstem hemangioblastomas

被引:18
作者
Chen, Li-feng [1 ]
Yang, Yang [2 ]
Yu, Xin-guang [1 ]
Bu, Bo [1 ]
Xu, Bai-nan [1 ]
Zhou, Ding-biao [1 ]
机构
[1] Chinese Peoples Liberat Army Gen Hosp, Dept Neurosurg, Beijing 100853, Peoples R China
[2] Chinese Peoples Liberat Army Gen Hosp, Dept Geriatr Neurol, Beijing 100853, Peoples R China
关键词
Brain stem; Hemangioblastoma; Microsurgery; HIPPEL-LINDAU-DISEASE; GAMMA-KNIFE RADIOSURGERY; SPINAL-CORD; INTRACRANIAL HEMANGIOBLASTOMAS; STEREOTACTIC RADIOSURGERY; SURGICAL-MANAGEMENT;
D O I
10.1016/j.jocn.2013.01.027
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Brainstem hemangioblastomas are technically challenging lesions. The authors retrospectively analyzed their experience in 24 patients with brainstem hemangioblastomas to evaluate the management strategies used over time and the results of microsurgical treatment. All patients were operated on between 2007 and 2012. The patients received postoperative follow-up by neuroradiological and neurological examinations. The maximum diameter of the tumors ranged from 2.0 to 4.5 cm (mean 3.6 cm). Gross total resection was achieved in 24 patients (100%). Two patients (8%) had new neurological deficits or worsening of pre-existing deficits. One patient (4%) died because of brain stem dysfunction after the operation. Radical en bloc surgical resection of brainstem hemangioblastomas in symptomatic patients is a safe and effective primary treatment. Preoperative embolization is not necessary. It is very important and necessary to differentiate and dissect precisely at the interface of the tumor surface and the brainstem with a meticulous microsurgical technique until the tumor is removed en bloc. The preoperative neurological status of the patient predicts the postoperative functional outcome. Asymptomatic patients with hemangioblastoma may be followed clinically with MRI surveillance at regular intervals. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1727 / 1733
页数:7
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