Management of benign skull base meninglomas: A review

被引:22
作者
Mendenhall, WM
Friedman, WA
Amdur, RJ
Foote, KD
机构
[1] Univ Florida, Coll Med, Dept Radiat Oncol, Gainesville, FL USA
[2] Univ Florida, Coll Med, Dept Neurosurg, Gainesville, FL USA
来源
SKULL BASE-AN INTERDISCIPLINARY APPROACH | 2004年 / 14卷 / 01期
关键词
neoplasm; skull base; treatment outcome; radiotherapy; radiosurgery; surgery;
D O I
10.1055/s-2004-821364
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The optimal management of benign meningiomas of the skull base is reviewed. Elderly patients with small, asymptomatic tumors can be observed and treatment can be initiated if and when progression occurs. Patients with tumors that appear to be amenable to complete resection with an acceptable rate of morbidity are optimally treated with surgery. Decompression of more extensive tumors through conservative subtotal resection and preservation of the involved cranial nerves may result in improved neurological function. Either alone or after subtotal resection, radiosurgery is indicated for tumors that can be treated adequately with this modality. Larger, ill-defined tumors and those that abut radiosensitive structures such as the optic nerve(s) are optimally treated with radiotherapy. Extensive subtotal resections that sacrifice one or more cranial nerves are no more likely to enhance the probability of success of subsequent radiotherapy than more conservative procedures.
引用
收藏
页码:53 / 60
页数:8
相关论文
共 35 条
[1]   MICROSURGICAL REMOVAL OF PETROCLIVAL MENINGIOMAS - A REPORT OF 33 PATIENTS [J].
BRICOLO, AP ;
TURAZZI, S ;
TALACCHI, A ;
CRISTOFORI, L ;
FUKUSHIMA, T ;
ALMEFTY, O .
NEUROSURGERY, 1992, 31 (05) :813-828
[2]   Benign meningiomas: Primary treatment selection affects survival [J].
Condra, KS ;
Buatti, JM ;
Mendenhall, WM ;
Friedman, WA ;
Marcus, RB ;
Rhoton, AL .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 39 (02) :427-436
[3]   Tumor size predicts control of benign meningiomas treated with radiotherapy [J].
Connell, PP ;
Macdonald, RL ;
Mansur, DB ;
Nicholas, MK ;
Mundt, AJ .
NEUROSURGERY, 1999, 44 (06) :1194-1199
[4]   Petroclival meningiomas: Surgical experience in 109 cases [J].
Couldwell, WT ;
Fukushima, T ;
Giannotta, SL ;
Weiss, MH .
JOURNAL OF NEUROSURGERY, 1996, 84 (01) :20-28
[5]  
De Monte F, 1995, Oncology (Williston Park), V9, P83
[6]   High efficacy of fractionated stereotactic radiotherapy of large base-of-skull meningiomas: Long-term results [J].
Debus, J ;
Wuendrich, M ;
Pirzkall, A ;
Hoess, A ;
Schlegel, W ;
Zuna, I ;
Engenhart-Cabillic, R ;
Wannenmacher, M .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (15) :3547-3553
[7]   Long-term follow-up of patients with meningiomas involving the cavernous sinus: Recurrence, progression, and quality of life [J].
DeJesus, O ;
Sekhar, LN ;
Parikh, HK ;
Wright, DC ;
Wagner, DP .
NEUROSURGERY, 1996, 39 (05) :915-919
[8]   OUTCOME OF AGGRESSIVE REMOVAL OF CAVERNOUS SINUS MENINGIOMAS [J].
DEMONTE, F ;
SMITH, HK ;
ALMEFTY, O .
JOURNAL OF NEUROSURGERY, 1994, 81 (02) :245-251
[9]   Long-term tumor control and functional outcome in patients with cavernous sinus meningiomas treated by radiotherapy with or without previous surgery:: Is there an alternative to aggressive tumor removal? [J].
Dufour, H ;
Muracciole, X ;
Métellus, P ;
Régis, J ;
Chinot, O ;
Grisoli, F .
NEUROSURGERY, 2001, 48 (02) :285-294
[10]  
FRIEDMAN WA, 1998, LINAC RADIOSURGERY P, P1