Oxidant-Responsive Induction of the suf Operon, Encoding a Fe-S Assembly System, through Fur and IscR in Escherichia coli

被引：76
|
作者：
Lee, Kyung-Chang
Yeo, Won-Sik
Roe, Jung-Hye [1 ]
机构：
[1] Seoul Natl Univ, Sch Biol Sci, Mol Microbiol Lab, Seoul 151742, South Korea
来源：
JOURNAL OF BACTERIOLOGY | 2008年 / 190卷 / 24期
关键词：
D O I：
10.1128/JB.01161-08
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The suf operon encoding a Fe-S assembly system is induced by peroxides through activators OxyR and IscR in Escherichia coli. For apo-IscR to bind, oxidation-mediated dissociation of Fur is required. Therefore, a peroxide-responsive signal is transduced through OxyR, IscR, and Fur to achieve oxidation-sensitive and maximal induction of this operon.
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收藏
页码：8244 / 8247
页数：4
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