Oxidant controlled regioselective mono- and di-functionalization reactions of coumarins

被引：81

作者：

Banerjee, Arghya ^{[1
]}

Santra, Sourav Kumar ^{[1
]}

Khatun, Nilufa ^{[1
]}

Ali, Wajid ^{[1
]}

Patel, Bhisma K. ^{[1
]}

机构：

[1] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, Assam, India

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 84期

关键词：

CATALYZED CARBONYLATION-PEROXIDATION; C-H FUNCTIONALIZATION; SIMPLE ALKANES; BOND FUNCTIONALIZATION; HECK REACTION; ALKENES; ACTIVATION; C(SP(3))-H; ALDEHYDES; ACCESS;

D O I：

10.1039/c5cc06200d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

C-3 alkylation of coumarins has been accomplished using cycloalkanes or alkylbenzenes in the presence of di-tert-butylperoxide (DTBP) and Fe-III catalyst. Under metal free conditions and just by switching the oxidant from DTBP to TBHP, an exclusive C-4 cycloalkylation-C-3 peroxidation reaction takes place. During C-3 alkylation, the C-C bond formation occurs at the expense of an existing C-C bond, while the C-4 alkylation is associated with the formation of new C-C and C-O bonds.

引用

页码：15422 / 15425

页数：4

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