Genetic Polymorphisms and Susceptibility to Sudden Sensorineural Hearing Loss: A Systematic Review

被引：15
作者：
Cao, Zaizai [1 ,2 ,3 ]
Gao, Jinjian [1 ,2 ,3 ]
Huang, Saiyu [1 ,2 ,3 ]
Xiang, Haijie [1 ,2 ,3 ]
Zhang, Chuqin [1 ,2 ,3 ]
Zheng, Bo [1 ,2 ,3 ]
Zhan, Xiang [1 ,2 ,3 ]
Chen, Ruru [1 ,2 ,3 ]
Chen, Bobei [1 ,2 ,3 ]
机构：
[1] Wenzhou Med Univ, Affiliated Hosp 2, Dept Otolaryngol, Coll West Rd 109, Wenzhou 325027, Peoples R China
[2] Wenzhou Med Univ, Yuying Childrens Hosp, Coll West Rd 109, Wenzhou 325027, Peoples R China
[3] Wenzhou Med Univ, Sch Med 2, Wenzhou, Peoples R China
来源：
AUDIOLOGY AND NEURO-OTOLOGY | 2019年 / 24卷 / 01期
关键词：
Sudden sensorineural hearing loss; Genetic polymorphisms; Susceptibility; Systematic review; Single nucleotide polymorphisms; FACTOR-V-LEIDEN; METHYLENETETRAHYDROFOLATE REDUCTASE GENE; PHOSPHODIESTERASE 4D GENE; ESTROGEN-RECEPTOR-ALPHA; RISK-FACTORS; ISCHEMIC-STROKE; MYOCARDIAL-INFARCTION; C677T POLYMORPHISM; MENIERES-DISEASE; ASSOCIATION;
D O I：
10.1159/000497032
中图分类号：
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号：
100104 ; 100213 ;
摘要：
Background: Recently, genetic factors have been considered as an important risk factor for sudden sensorineural hearing loss (SSNHL). Many studies analyzed the association between SSNHL and polymorphisms. However, most of them gave inconclusive results. KeyMessage: We performed a systematic review to find out the association between polymorphisms and susceptibility to SSNHL. Finally, 47 studies involving 5,230 SSNHL patients and 68 genes were included for analysis and discussion of results. Polymorphisms in 26 genes have been suggested to be correlated with the susceptibility to SSNHL. Summary: Although a great number of studies support that polymorphisms in genes are associated with susceptibility to SSNHL, we need large multicenter studies, which evaluate multiple single nucleotide polymorphisms in SSNHL patients, to find real genetic risk factors for susceptibility to SSNHL. This is very helpful in designing more effective prevention and treatment strategies for patients with SSNHL. (C) 2019 S. Karger AG, Basel
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页码：8 / 19
页数：12
相关论文
共 84 条
  • [11] The influence of genetic variation in oxidative stress genes on human noise susceptibility
    Carlsson, PI
    Van Laer, L
    Borg, E
    Bondeson, ML
    Thys, M
    Fransen, E
    Van Camp, G
    [J]. HEARING RESEARCH, 2005, 202 (1-2) : 87 - 96
  • [12] Castiglione A., 2015, BIOMED RES INT, V2015, DOI DOI 10.1155/2015/834736
  • [13] Systematic Review of the Evidence for the Etiology of Adult Sudden Sensorineural Hearing Loss
    Chau, Justin K.
    Lin, June R. J.
    Atashband, Shahnaz
    Irvine, Robert A.
    Westerberg, Brian D.
    [J]. LARYNGOSCOPE, 2010, 120 (05) : 1011 - 1021
  • [14] Glutathione peroxidase 3 gene polymorphisms and the risk of sudden sensorineural hearing loss
    Chien, Chen-Yu
    Huang, Tzu-Yen
    Tai, Shu-Yu
    Chang, Ning-Chia
    Wang, Hsun-Mo
    Wang, Ling-Feng
    Ho, Kuen-Yao
    [J]. KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, 2017, 33 (07) : 359 - 364
  • [15] Phosphodiesterase 4D gene polymorphisms in sudden sensorineural hearing loss
    Chien, Chen-Yu
    Tai, Shu-Yu
    Wang, Ling-Feng
    Hsi, Edward
    Chang, Ning-Chia
    Wang, Hsun-Mo
    Wu, Ming-Tsang
    Ho, Kuen-Yao
    [J]. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2016, 273 (09) : 2403 - 2409
  • [16] Heat Shock Protein 70 Gene Polymorphisms in Sudden Sensorineural Hearing Loss
    Chien, Chen-Yu
    Chang, Ning-Chia
    Tai, Shu-Yu
    Wang, Ling-Feng
    Wu, Ming-Tsang
    Ho, Kuen-Yao
    [J]. AUDIOLOGY AND NEURO-OTOLOGY, 2012, 17 (06) : 381 - 385
  • [17] Cho SH, 2012, EAR NOSE THROAT DISO, V12, P1
  • [18] Sudden Sensorineural Hearing Loss Associated With Iron-Deficiency Anemia A Population-Based Study
    Chung, Shiu-Dong
    Chen, Po-Yueh
    Lin, Herng-Ching
    Hung, Shih-Han
    [J]. JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2014, 140 (05) : 417 - 422
  • [19] MMP-1 promoter polymorphism: association with chronic periodontitis severity in a Brazilian population
    de Souza, AP
    Trevilatto, PC
    Scarel-Caminaga, RM
    Brito, RB
    Line, SRP
    [J]. JOURNAL OF CLINICAL PERIODONTOLOGY, 2003, 30 (02) : 154 - 158
  • [20] ELBARBARY A, 1993, HEARING RES, V71, P80
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