Ultra-high-resolution SD-OCM imaging with a compact polarization-aligned 840 nm broadband combined-SLED source

被引：13

作者：

Haindl, Richard ^{[1
,4
]}

Duelk, Marcus ^{[2
]}

Gloor, Stefan ^{[2
]}

Dahdah, Jean ^{[2
]}

Ojeda, Jose ^{[2
]}

Sturtzel, Caterina ^{[3
]}

Deng, Shiyu ^{[1
]}

Deloria, Abigail Joyce ^{[1
]}

Li, Qian ^{[1
]}

Liu, Mengyang ^{[1
]}

Distel, Martin ^{[3
]}

Drexler, Wolfgang ^{[1
]}

Leitgeb, Rainer ^{[1
]}

机构：

[1] Med Univ Vienna, Ctr Med Phys & Biomed Engn, Vienna, Austria

[2] EXALOS AG, Wagistr 21, CH-8952 Schlieren, Switzerland

[3] Childrens Canc Res Inst, Innovat Canc Models, Vienna, Austria

[4] Med Univ Vienna, Christian Doppler Lab OPTRAMED, Vienna, Austria

来源：

BIOMEDICAL OPTICS EXPRESS | 2020年 / 11卷 / 06期

关键词：

OPTICAL COHERENCE TOMOGRAPHY; MODE DISPERSION; SENSITIVE OCT; LASER; WAVELENGTH; ARTIFACTS;

D O I：

10.1364/BOE.394229

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We analyze the influence of intrinsic polarization alignment on image quality and axial resolution employing a broadband 840 nm light source with an optical bandwidth of 160 nm and an output power of 12 mW tailored for spectral-domain optical coherence microscopy (SD-OCM) applications. Three superluminescent diodes (SLEDs) are integrated into a 14-pin butterfly module using a free-space micro-optical bench architecture, maintaining a constant polarization state across the full spectral output. We demonstrate superior imaging performance in comparison to traditionally coupled-SLED broadband light sources in a teleost model organism in-vivo. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

引用

页码：3395 / 3406

页数：12

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