Phospholipid composition of high-density lipoproteins reflects lipolysis of triglyceride-rich lipoproteins during hyperlipidemia

被引：2

作者：

Perova, NV ^{[1
]}

Ozerova, IN ^{[1
]}

Paramonova, IV ^{[1
]}

Olfer'ev, AM ^{[1
]}

Akhmedzhanov, NM ^{[1
]}

Pavlova, LI ^{[1
]}

Oganov, RG ^{[1
]}

机构：

[1] Russian Minist Hlth, State Res Ctr Prevent Med, Dept Metab Dis, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2001年 / 131卷 / 04期

关键词：

lipoproteins; phospholipids; lipoprotein lipase; hepatic lipase;

D O I：

10.1023/A:1017983615183

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We studied phospholipid composition of high-density lipoproteins in patients with normo- and hypertriglyceridemia treated with various hypolipidemic preparations (simvastatin and fenofibrate). Both preparations changed phospholipid composition of high-density lipoproteins and improved their functional activity. The differences in the phospholipid composition of high-density lipoproteins were probably related to lipolysis of triglyceride-rich lipoproteins catalyzed by lipoprotein lipase and, in particular, hepatic lipase.

引用

页码：321 / 324

页数：4

共 16 条

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