Statistical description for survival data

被引:8
作者
Zhang, Zhongheng [1 ]
机构
[1] Zhejiang Univ, Jinhua Hosp, Jinhua Municipal Cent Hosp, Dept Crit Care Med, 351 Mingyue Rd, Jinhua 321000, Zhejiang, Peoples R China
关键词
Survival analysis; parametric model; Kaplan-Meier; log-rank; POINTWISE CONFIDENCE-INTERVALS;
D O I
10.21037/atm.2016.07.17
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Statistical description is always the first step in data analysis. It gives investigator a general impression of the data at hand. Traditionally, data are described as central tendency and deviation. However, this framework does not fit to the survival data (also termed time-to-event data). Such data type contains two components. One is the survival time and the other is the status. Researchers are usually interested in the probability of event at a given survival time point. Hazard function, cumulative hazard function and survival function are commonly used to describe survival data. Survival function can be estimated using Kaplan-Meier estimator, which is also the default method in most statistical packages. Alternatively, Nelson-Aalen estimator is available to estimate survival function. Survival functions of subgroups can be compared using log-rank test. Furthermore, the article also introduces how to describe time-to-event data with parametric modeling.
引用
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页数:7
相关论文
共 14 条
[1]   NONPARAMETRIC INFERENCE FOR A FAMILY OF COUNTING PROCESSES [J].
AALEN, O .
ANNALS OF STATISTICS, 1978, 6 (04) :701-726
[2]   SIMULTANEOUS NONPARAMETRIC CONFIDENCE-INTERVALS FOR SURVIVAL PROBABILITIES FROM CENSORED-DATA [J].
AFIFI, AA ;
ELASHOFF, RM ;
LEE, JJ .
STATISTICS IN MEDICINE, 1986, 5 (06) :653-662
[3]  
Ahmed N, 2015, LIFETIME DATA ANAL
[4]  
David KG, 2006, BIOMETRICS, V62, P312
[5]   Finite sample pointwise confidence intervals for a survival distribution with right-censored data [J].
Fay, Michael P. ;
Brittain, Erica H. .
STATISTICS IN MEDICINE, 2016, 35 (16) :2726-2740
[6]   Pointwise confidence intervals for a survival distribution with small samples or heavy censoring [J].
Fay, Michael P. ;
Brittain, Erica H. ;
Proschan, Michael A. .
BIOSTATISTICS, 2013, 14 (04) :723-736
[7]  
HALL WJ, 1980, BIOMETRIKA, V67, P133
[8]   A CLASS OF RANK TEST PROCEDURES FOR CENSORED SURVIVAL-DATA [J].
HARRINGTON, DP ;
FLEMING, TR .
BIOMETRIKA, 1982, 69 (03) :553-566
[9]  
Lindsey JC, 1998, STAT MED, V17, P219, DOI 10.1002/(SICI)1097-0258(19980130)17:2<219::AID-SIM735>3.0.CO
[10]  
2-O