Synthesis, characterization and biological activity of ferrocene-based Schiff base ligands and their metal (II) complexes

被引：82

作者：

Liu, Yu-Ting ^{[1
]}

Lian, Gui-Dan ^{[1
]}

Yin, Da-Wei ^{[1
]}

Su, Bao-Jun ^{[1
]}

机构：

[1] Shaanxi Univ Sci & Technol, Minist Educ, Key Lab Auxiliary Chem & Technol Chem Ind, Xian 710021, Shaanxi, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2013年 / 100卷

关键词：

Synthesis; Schiff bases; Antibacterial activity; Antifungal activity; COPPER(II) COMPLEXES; NICKEL(II) COMPLEXES; ANTIBACTERIAL; PROPERTY; CR(III); FE(III);

D O I：

10.1016/j.saa.2012.03.049

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Metal (II) complexes derived from S-benzyl-N-(1-ferrocenyl-3-(4-methylbenzene)acrylketone) dithiocarbazate; HL1, S-benzyl-N-(1-ferrocenyl-3-(4-chlorobenzene)acrylketone)dithiocarbazate; HL2, all the compounds were characterized using various spectroscopic techniques. The molar conductance data revealed that the chelates were non-electrolytes. IR spectra showed that the Schiff bases were coordinated to the metal ions in a bidentate manner with N, S donor sites. The ligands and their metal complexes have been screened for in vitro antibacterial, antifungal properties. The result of these studies have revealed that zinc (II) complexes 6 and 13 of both the ligands and copper (II) complexes 9 of the HL2 were observed to be the most active against all bacterial strains, antifungal activity was overall enhanced after complexation of the ligands. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：131 / 137

页数：7

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