Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry

被引:79
作者
Krogh, K. A. [1 ,2 ]
Bjorklund, E. [1 ]
Loeffler, D. [2 ]
Fink, G. [2 ]
Halling-Sorensen, B. [1 ]
Ternes, T. A. [2 ]
机构
[1] Univ Copenhagen, Fac Pharmaceut Sci, Dept Pharmaceut & Analyt Chem, Sect Toxicol & Environm Chem, DK-2100 Copenhagen, Denmark
[2] Fed Inst Hydrol, D-56068 Koblenz, Germany
关键词
Avermectins; Parasiticides; Solid-phase extraction; Pressurised liquid extraction; Water; Sediment; Soil;
D O I
10.1016/j.chroma.2008.09.081
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A comprehensive analytical multi-residue method has been developed for the determination of seven avermectins (abamectin, doramectin, ivermectin, emamectin benzoate. eprinomectin, moxidectin and selamectin) in surface water, sediment and soil samples. Solid samples were extracted applying pressurised liquid extraction followed by a solid-phase extraction (SPE) clean-up step. For aqueous samples, extraction was done utilising Only SPE. All Compounds were measured using liquid chromatography coupled to tandem mass spectrometry using atmospheric pressure chemical ionisation. The recoveries were 38-67% (relative standard deviation: 9-26%), 63-88% (16-23%) and 63-80% (9-15%) for spiked Rhine water, spiked sediment and spiked soil samples, respectively, and limit of quantifications were 2.5-14 ng l(-1) in water and 0.5-2.5 ng g(-1) in soil and sediment. (C) 2008 Elsevier B.V. All rights reserved.
引用
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页码:60 / 69
页数:10
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