Auto-redox reaction:: Tin(II) chloride-mediated one-step reductive cyclization leading to the synthesis of novel biheterocyclic 5,6-dihydro-quinazolino[4,3-b]quinazolin-8-ones with three-point diversity

被引：73

作者：

Roy, AD ^{[1
]}

Subramanian, A ^{[1
]}

Roy, R ^{[1
]}

机构：

[1] Cent Drug Res Inst, Div SAIF, Lucknow 226001, Uttar Pradesh, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 01期

关键词：

D O I：

10.1021/jo0518912

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A tin(II) chloride-mediated short, efficient, and practical regioselective synthesis of biheterocyclic 5,6-dihydro-quinazolino[4,3-b]quinazolin-8-ones with three-point diversity is reported. A one-step reductive transformation of 2-(2-nitrophenyl)-3H-quinazolin-4-one in various alcohols furnished the desired tetracyclic product in good yields with high purity.

引用

页码：382 / 385

页数：4

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