Gustation assessment using the NIH Toolbox

被引：79

作者：

Coldwell, Susan E. ^{[1
]}

Mennella, Julie A. ^{[2
]}

Duffy, Valerie B. ^{[3
]}

Pelchat, Marcia L. ^{[2
]}

Griffith, James W. ^{[4
]}

Smutzer, Gregory ^{[5
]}

Cowart, Beverly J. ^{[2
]}

Breslin, Paul A. S. ^{[2
,6
]}

Bartoshuk, Linda M. ^{[7
]}

Hastings, Lloyd ^{[8
]}

Victorson, David ^{[4
]}

Hoffman, Howard J. ^{[9
]}

机构：

[1] Univ Washington, Sch Dent, Seattle, WA 98195 USA

[2] Monell Chem Senses Ctr, Philadelphia, PA 19104 USA

[3] Univ Connecticut, Coll Agr & Nat Resources, Storrs, CT USA

[4] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA

[5] Temple Univ, Philadelphia, PA 19122 USA

[6] Rutgers State Univ, Sch Environm & Biol Sci, New Brunswick, NJ 08903 USA

[7] Univ Florida, Gainesville, FL USA

[8] Osmic Enterprises Inc, Cincinnati, OH USA

[9] Natl Inst Deafness & Other Commun Disorders, Bethesda, MD USA

来源：

NEUROLOGY | 2013年 / 80卷

关键词：

BITTER TASTE; PERCEPTION; SENSITIVITY; PREFERENCES; GENETICS; CHILDREN; DAMAGE;

D O I：

10.1212/WNL.0b013e3182872e38

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The NIH Toolbox for Assessment of Neurological and Behavioral Function (NIH Toolbox) is a set of brief measures for the assessment of cognitive function, emotional health, motor function, and sensory function for use in clinical trials and in epidemiologic and longitudinal studies. Gustatory perception is assessed as 1 of 6 areas of sensory function. A team of 11 scientists with expertise in taste perception selected 2 gustatory measures, 1 of which can be used in young pediatric populations. The measure selected for young pediatric populations assesses sucrose (sweet) taste preference and can also be used across the age span of 5 to 85 years. For adult populations, the selected measure is a regional test, which assesses variability in perceived intensity of quinine hydrochloride (bitter) when applied to the tongue tip as well as perceived with the whole mouth. The team also recommends the regional test for assessing other tastants, such as sodium chloride (salty). Validation studies have demonstrated that the measures modified for the NIH Toolbox correlate with more traditional assessments, and can identify known population differences in gustation. Neurology (R) 2013; 80 (Suppl 3):S20-S24

引用

页码：S20 / S24

页数：5

共 23 条

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