Pulmonary thromboembolism after air travel: Two case reports, the review of literature and forensic implications

被引：0

作者：

Mihailovic, Zoran ^{[1
]}

Radnic, Bojana ^{[1
]}

Atanasijevic, Tatjana ^{[1
]}

Popovic, Vesna ^{[1
]}

机构：

[1] Univ Belgrade, Sch Med, Inst Forens Med Milovan Milovanov, Belgrade 11000, Serbia

来源：

FORENSIC SCIENCE INTERNATIONAL | 2012年 / 222卷 / 1-3期

关键词：

Pulmonary thromboembolism; Air travel; Autopsy; DEEP-VEIN THROMBOSIS; VENOUS THROMBOEMBOLISM; COAGULATION ACTIVATION; BIOCHEMICAL MARKERS; HYPOBARIC HYPOXIA; RISK-FACTOR; EMBOLISM; EDEMA; ASSOCIATION; PREVENTION;

D O I：

10.1016/j.forsciint.2012.05.016

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Air travel as a risk factor for pulmonary thromboembolism (PTE) is rarely described in forensic literature. Two cases of PTE after air travel are presented in this report. Each flight was intercontinental and lasted for more than 10 h, resulting in typical "traveler's thrombosis" within 2 weeks. In both cases, the risk factors were age, duration of flight and also peripheral circulation problems caused by heart (hypertension, arrhythmia), and varicose veins failures. Possible pathophysiological mechanisms of thrombus formation in these cases were blood flow stasis from prolonged recumbence, reduced function of the lower leg muscle pump, dehydration, and hypobaric hypoxia. Legal aspects of death due to PTE after air travel and possible responsibility of air companies are discussed. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

引用

页码：E13 / E18

页数：6

共 40 条

[1] The association between seated immobility and local lower-limb venous coagulability in healthy adult volunteers: a simulation of prolonged travel immobility
Ansari, Mohammed T.
Mahmood, Mohammad T.
Karlberg, Johan P. E.
[J]. BLOOD COAGULATION & FIBRINOLYSIS, 2006, 17 (05) : 335 - 341
[2] Long-haul flights and deep vein thrombosis: a significant risk only when additional factors are also present
Arya, R
Barnes, JA
Hossain, U
Patel, RK
Cohen, AT
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2002, 116 (03) : 653 - 654
[3] Diagnosis of DVT Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Bates, Shannon M.
Jaeschke, Roman
Stevens, Scott M.
Goodacre, Steve
Wells, Philip S.
Stevenson, Matthew D.
Kearon, Clive
Schunemann, Holger J.
Crowther, Mark
Pauker, Stephen G.
Makdissi, Regina
Guyatt, Gordon H.
[J]. CHEST, 2012, 141 (02) : E351S - E418S
[4] Prevention of edema, flight microangiopathy and venous thrombosis in long flights with elastic stockings. A Randomized trial: The LONFLIT 4 concorde Edema-SSL study
Belcaro, G
Cesarone, MR
Shah, SSG
Nicolaides, AN
Geroulakos, G
Ippolito, E
Winford, M
Lennox, A
Pellegrini, L
Brandolini, R
Myers, KA
Simeone, E
Bavera, P
Dugall, M
Di Renzo, A
Moia, M
[J]. ANGIOLOGY, 2002, 53 (06) : 635 - 645
[5] Association between acute hypobaric hypoxia and activation of coagulation in human beings
Bendz, B
Rostrup, M
Sevre, K
Andersen, TO
Sandset, PM
[J]. LANCET, 2000, 356 (9242) : 1657 - 1658
[6] Bocalon H., 2003, J THROMB HAEMOST, V3, P1539
[7] Travel-related venous thrombosis: Results from a large population-based case control study (MEGA study)
Cannegieter, Suzanne C.
Doggen, Carine J. M.
van Houwelingen, Hans C.
Rosendaal, Frits R.
[J]. PLOS MEDICINE, 2006, 3 (08) : 1258 - 1265
[8] Venous thrombosis from air travel: The LONFLIT3 study - Prevention with aspirin vs low-molecular-weight heparin (LMWH) in high-risk subjects: A randomized trial
Cesarone, MR
Belcaro, G
Nicolaides, AN
Incandela, L
De Sanctis, MT
Geroulakos, G
Lennox, A
Myers, KA
Moia, M
Ippolito, E
Winford, M
[J]. ANGIOLOGY, 2002, 53 (01) : 1 - 6
[9] Air travel and thrombosis
Chee, YL
Watson, HG
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2005, 130 (05) : 671 - 680
[10] Relation between acute hypoxia and activation of coagulation in human beings
Crosby, A
Talbot, NP
Harrison, P
Keeling, D
Robbins, PA
[J]. LANCET, 2003, 361 (9376) : 2207 - 2208

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