Ruthenium-Catalyzed Pyrrole Synthesis via Oxidative Annulation of Enamides and Alkynes

被引：148
作者：
Li, Bin [1 ]
Wang, Nuancheng [1 ]
Liang, Yujie [1 ]
Xu, Shansheng [1 ]
Wang, Baiquan [1 ,2 ]
机构：
[1] Nankai Univ, State Key Lab Element Organ Chem, Coll Chem, Tianjin 300071, Peoples R China
[2] Chinese Acad Sci, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 01期
关键词：
H BOND ACTIVATION; REGIOSELECTIVE SYNTHESIS; SUBSTITUTED PYRROLES; EFFICIENT SYNTHESIS; CYCLIZATION; AMINES; FUNCTIONALIZATIONS; INDOLES; IMINES; COPPER;
D O I：
10.1021/ol303159h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient and regioselective ruthenium-catalyzed oxidative annulation of enamides with alkynes via the cleavage of C(sp(2))-H/N-H bonds is reported. The reactions can afford N-acetyl substituted or N-unsubstituted pyrroles by altering the reaction conditions slightly.
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页码：136 / 139
页数：4
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