How to Modulate the Chemical Structure of Polyoxazolines by Appropriate Functionalization

被引：187

作者：

Guillerm, Brieuc ^{[1
]}

Monge, Sophie ^{[1
]}

Lapinte, Vincent ^{[1
]}

Robin, Jean-Jacques ^{[1
]}

机构：

[1] Univ Montpellier 2, Equipe Ingn & Architectures Macromol, CNRS,ENSCM, Inst Charles Gerhardt Montpellier UMR5253,UM2,UM1, F-34095 Montpellier 5, France

来源：

MACROMOLECULAR RAPID COMMUNICATIONS | 2012年 / 33卷 / 19期

关键词：

cationic polymerization; functionalization of polymers; oligomers; ring-opening polymerization; RING-OPENING POLYMERIZATION; LIVING CATIONIC-POLYMERIZATION; ISOMERIZATION POLYMERIZATION; BLOCK-COPOLYMERS; POLY(N-ACYLETHYLENIMINE) COPOLYMERS; SATELLITE GROUPS; CLICK CHEMISTRY; STAR POLYMERS; CROSS-LINKING; POLY(2-OXAZOLINE)S;

D O I：

10.1002/marc.201200266

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Polyoxazolines (POx) are increasingly being studied as polymeric building blocks due to the possibility of affording tunable properties. Additionally, as the biocompatibility and stealth behavior of POx are similar to that of poly(ethylene glycol) (PEG), it has become challenging to develop polyoxazoline-based (co)polymers. Even if POx have a lot of advantages, they also show an important drawback, as it has been impossible, to date, to prepare high-molecular-weight polyoxazolines with a low polydispersity index. Thus, it appears important that they be judiciously functionalized. This review covers the multiple ways that polyoxazolines can be functionalized. The use of functional initiators, functional terminating agents, and 2-R-2-oxazolines with an R functional side group is detailed. In conclusion, some perspectives on POx functionalizations are also reported, with functions permitting selective click reactions.

引用

页码：1600 / 1612

页数：13

共 142 条

[1] Poly(2-oxazolines) in biological and biomedical application contexts [J].