Benzophenone glycosides and epicatechin derivatives from Malania oleifera

被引:24
作者
Wu, Xing-De [2 ,3 ]
Cheng, Jin-Tang [2 ,3 ]
He, Juan [2 ]
Zhang, Xing-Jie [3 ,4 ,5 ]
Dong, Liao-Bin [2 ,3 ]
Gong, Xun [2 ]
Song, Liu-Dong [1 ]
Zheng, Yong-Tang [4 ,5 ]
Peng, Li-Yan [2 ]
Zhao, Qin-Shi [2 ]
机构
[1] Kunming Med Univ, Coll Pharmacol, Kunming 650031, Peoples R China
[2] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
[3] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
[4] Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan Province, Peoples R China
[5] Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Yunnan Province, Peoples R China
基金
中国国家自然科学基金;
关键词
Malania oleifera; Benzophenone C-glycoside; Epicatechin derivatives; Anti-HIV activities; POLYPHENOLS;
D O I
10.1016/j.fitote.2012.05.006
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new benzophenone C-glycoside, malaferin A (1), and two new epicatechin derivatives. malaferin B (2) and malaferin C (3), together with five known compounds were isolated from Malania oleifera. In addition, ()-epicatechin-3-O-benzoate (6) was isolated for the first time from a natural resource. Structures of 1-3 were determined on the basis of their spectroscopic methods, including 1D and 2D NMR techniques. All of the compounds were evaluated for anti-HIV activities. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:1068 / 1071
页数:4
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