GENOTYPE IDENTIFICATION ENTEROCYTOZOON BIENEUSI ISOLATES FROM STOOL SAMPLES OF HIV-INFECTED TUNISIAN PATIENTS

被引：14
作者：
Chabchoub, N. [1 ,2 ]
Abdelmalek, R. [1 ,2 ,3 ]
Breton, J. [4 ]
Kanoun, F. [1 ,2 ,3 ]
Thellier, M. [4 ]
Bouratbine, A. [1 ,2 ]
Aoun, K. [1 ,2 ]
机构：
[1] Inst Pasteur Tunis, Parasitol Lab, Tunis 1002, Tunisia
[2] Inst Pasteur Tunis, Lab Rech Parasitoses Med Biotechnol & Biomol LR 1, Tunis 1002, Tunisia
[3] Hop Rabta, Serv Malad Infect, Tunis, Tunisia
[4] Univ Paris 06, INSERM, Hop La Pitie Salpetriere, U511, Paris, France
来源：
PARASITE | 2012年 / 19卷 / 02期
关键词：
microsporidia; Enterocytozoon bieneusi; genotype; Internal Transcribed Spacer; HIV; Tunisia; INTESTINAL MICROSPORIDIOSIS; AIDS PATIENTS; PREVALENCE; SEQUENCE; DIARRHEA; STRAINS; HUMANS; AREAS;
D O I：
10.1051/parasite/2012192147
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The microsporidian species Enterocytozoon bieneusi is a major cause of chronic diarrhea and malabsorption in patients with AIDS. Genotyping was performed on seven E. bieneusi strains for the first time in Tunisia. All the strains were isolated from stool samples of humans with immunodeficiency virus (HIV) infection. Analysis of the ribosomal RNA gene internal transcribed spacer (rDNA ITS) allowed the identification of three distinct genotypes previously described in other studies. Genotypes D and 13 were characterized in four and two respectively. The Peruvian genotype (Peru 8) was detected in the last isolate. These results indicate a genetic diversity in E. bieneusi strains from HIV Tunisian patients and suggest the coexistence of both zoonotic and anthroponotic route of transmission.
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页码：147 / 151
页数：5
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