Safety and Efficacy of First-in-human Clinical Trial of Intrathecal Transplantation of Human Astrocytes (AstroRx) Derived from hESC in ALS Patients

被引：0

作者：

Izrael, Michal ^{[1
]}

Gotkine, Marc ^{[2
]}

Lerner, Yossef ^{[2
]}

Slutsky, Guy Shalom ^{[3
]}

Chebath, Judith ^{[3
]}

Caraco, Yoseph ^{[4
]}

Ben-Hur, Tamir ^{[2
]}

Hasson, Arik ^{[3
]}

Sonnenfeld, Tehila ^{[5
]}

Revel, Michel ^{[3
]}

机构：

[1] Kadimastem Ltd, Ness Ziona, Israel

[2] Hadassah Med Ctr, Neurol Dept, Jerusalem, Israel

[3] Kadimastem Ltd, Ness Ziona, Israel

[4] Hadassah Med Ctr, HCRC, Jerusalem, Israel

[5] Kadimastem Ltd, Jerusalem, Israel

来源：

MUSCLE & NERVE | 2022年 / 66卷

关键词：

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

107

引用

页码：S48 / S48

页数：1

共 50 条

[31] First-in-Human Clinical Trial of Oral ONC201 in Patients with Refractory Solid Tumors [J].

Stein, Mark N. ;

Bertino, Joseph R. ;

Kaufman, Howard L. ;

Mayer, Tina ;

Moss, Rebecca ;

Silk, Ann ;

Chan, Nancy ;

Malhotra, Jyoti ;

Rodriguez, Lorna ;

Aisner, Joseph ;

Aiken, Robert D. ;

Haffty, Bruce G. ;

DiPaola, Robert S. ;

Saunders, Tracie ;

Zloza, Andrew ;

Damare, Sherri ;

Beckett, Yasmeen ;

Yu, Bangning ;

Najmi, Saltanat ;

Gabel, Christian ;

Dickerson, Siobhan ;

Zheng, Ling ;

El-Deiry, Wafik S. ;

Allen, Joshua E. ;

Stogniew, Martin ;

Oster, Wolfgang ;

Mehnert, Janice M. .

CLINICAL CANCER RESEARCH, 2017, 23 (15) :4163-4169

[32] Evaluating the First-in-Human Clinical Trial of a Human Embryonic Stem Cell-Based Therapy [J].

Chapman, Audrey R. ;

Scala, Courtney C. .

KENNEDY INSTITUTE OF ETHICS JOURNAL, 2012, 22 (03) :243-261

[33] Trends in First-in-Human Studies for Intrathecal Antisense Oligonucleotides: Insights From 2010 to 2024 [J].

Schmitz, Natalie ;

Abdelmageed, Mai M. ;

Monine, Michael ;

Xu, Yan .

JOURNAL OF CLINICAL PHARMACOLOGY, 2025,

[34] First-in-human phase I study to assess safety, tolerability and dose for intrathecal injection of ISIS-SMNRx in SMA patients [J].

Swoboda, K. ;

Chiriboga, C. ;

Darras, B. ;

Iannaccone, S. ;

Montes, J. ;

Rausch, N. ;

Parad, R. ;

Johnson, S. ;

De Vivo, D. ;

Norris, D. ;

Alexander, K. ;

Bennet, F. C. ;

Bishop, K. .

NEUROMUSCULAR DISORDERS, 2013, 23 (9-10) :797-798

[35] Applicability and Safety of a Regulatory T Cell Therapy in Adult Liver Transplantation: The "ThRIL" Phase I First-in-Human Trial [J].

Whitehouse, G. ;

Safinia, N. ;

Thirkell, S. ;

Fry, L. ;

Grageda, N. ;

Martinez-Llordella, M. ;

Lechler, R. ;

Heaton, N. ;

Lombardi, G. ;

Sanchez-Fueyo, A. .

AMERICAN JOURNAL OF TRANSPLANTATION, 2017, 17 :277-278

[36] First-in-Human Trial of Epichaperome-Targeted PET in Patients with Cancer [J].

Dunphy, Mark P. S. ;

Pressl, Christina ;

Pillarsetty, Nagavarakishore ;

Grkovski, Milan ;

Modi, Shanu ;

Jhaveri, Komal ;

Norton, Larry ;

Beattie, Bradley J. ;

Zanzonico, Pat B. ;

Zatorska, Danuta ;

Taldone, Tony ;

Ochiana, Stefan O. ;

Uddin, Mohammad M. ;

Burnazi, Eva M. ;

Lyashchenko, Serge K. ;

Hudis, Clifford A. ;

Bromberg, Jacqueline ;

Schoder, Heiko M. ;

Fox, Josef J. ;

Zhang, Hanwen ;

Chiosis, Gabriela ;

Lewis, Jason S. ;

Larson, Steven M. .

CLINICAL CANCER RESEARCH, 2020, 26 (19) :5178-5187

[37] First-in-human exploratory trial assessing safety, feasibility, and efficacy of artificial protein (silk-elastin) in promoting healing in patients with meniscus injuries [J].

Ishikawa, Masakazu ;

Tsuji, Shunya ;

Kamei, Goki ;

Nakata, Kyohei ;

Nekomoto, Akinori ;

Hashiguchi, Naofumi ;

Nakasa, Tomoyuki ;

Nakamae, Atsuo ;

Kamei, Naosuke ;

Inoue, Keiichiro ;

Kawabata, Shingo ;

Ueda, Keiko ;

Adachi, Nobuo .

SCIENTIFIC REPORTS, 2025, 15 (01)

[38] ROBOTIC BLADDER AUTOTRANSPLANTATION: PRECLINICAL STUDIES IN PREPARATION FOR FIRST-IN-HUMAN TRIAL OF BLADDER TRANSPLANTATION [J].

Nassiri, Nima ;

Cacciamani, Giovanni ;

Ginsberg, David ;

Kreydin, Evgeniy ;

Abreu, Andre ;

Desai, Mihir ;

Aron, Monish ;

Qazi, Yasir ;

Genyk, Yuri ;

Gill, Inderbir .

JOURNAL OF UROLOGY, 2023, 209 :E892-E892

[39] Photochemical tissue bonding for closure of excision wounds: a first-in-human clinical trial [J].

Tsao, S. ;

Yao, M. ;

Henry, F. P. ;

Tsao, H. ;

Redmond, R. W. ;

Kochevar, I. E. .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 :S47-S47

[40] Efficacy and Safety of Novel NovaCross Microcatheter for Chronic Total Occlusions: First-in-Human Study [J].

Walsh, Simon ;

Dudek, Dariusz ;

Bryniarski, Leszek ;

Assali, Abid ;

Danenberg, Haim ;

Lotan, Chaim ;

Hanratty, Colm ;

Wilkolek, Piotr ;

Kornowski, Ran .

JOURNAL OF INVASIVE CARDIOLOGY, 2016, 28 (03) :88-91

← 1 2 3 4 5 →