Automated production of 16α-[18F]fluoroestradiol for breast cancer imaging

被引：43
|
作者：
Römer, J [1 ]
Füchtner, F [1 ]
Steinbach, J [1 ]
Johanssen, B [1 ]
机构：
[1] Rossendorf Inc, Forschungszentrum Rossendorf EV, Inst Bioanorgan & Radiopharmazeut Chem, D-01314 Dresden, Germany
来源：
NUCLEAR MEDICINE AND BIOLOGY | 1999年 / 26卷 / 04期
关键词：
D O I：
10.1016/S0969-8051(98)00098-5
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
The results show that it was possible to apply the safe and reproducible process of preparation of chemically and radiochemically pure 16α-[18F]FES to an automatic module. The modified [18F]FDG module from Nuclear Interface proved to be suitable for this method. An automatic module and a production plant make it possible to work with an amount of radioactivity of up to 100 GBq. Thus, there is nothing to impede the regular production of 16α- [18F]FES as a radiopharmaceutical in amounts that permit application to several breast cancer patients.
引用
收藏
页码：473 / 479
页数：7
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