Roles of microRNAs in the Hepatitis B Virus Infection and Related Diseases

被引：29
作者：
Thirion, Muriel [1 ]
Ochiya, Takahiro [1 ]
机构：
[1] Natl Canc Ctr, Res Inst, Div Mol & Cellular Med, Chuo Ku, Tokyo 1040045, Japan
来源：
VIRUSES-BASEL | 2013年 / 5卷 / 11期
关键词：
hepatitis B virus; microRNA; hepatocellular carcinoma; HEPATOCELLULAR-CARCINOMA; LIVER-CANCER; EPIGENETIC REGULATION; VIRAL REPLICATION; RNA ABUNDANCE; CELLULAR-DNA; X PROTEIN; EXPRESSION; TARGETS; GENE;
D O I：
10.3390/v5112690
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The hepatitis B virus (HBV) is a small enveloped DNA virus that belongs to the Hepadnaviridae family. HBV can cause acute and persistent infection which can lead to hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play a crucial role in the main cellular events. The dysregulation of their expression has been linked to the development of the cancer as well as to viral interference. This chapter will describe the involvement of miRNAs in the case of HBV infection and their implication in the development of the HBV-related diseases.
引用
收藏
页码：2690 / 2703
页数：14
相关论文
共 72 条
[51]   Human microRNA hsa-miR-125a-5p interferes with expression of hepatitis B virus surface antigen [J].
Potenza, Nicoletta ;
Papa, Umberto ;
Mosca, Nicola ;
Zerbini, Francesca ;
Nobile, Valentina ;
Russo, Aniello .
NUCLEIC ACIDS RESEARCH, 2011, 39 (12) :5157-5163
[52]   miR-122-induced down-regulation of HO-1 negatively affects miR-122-mediated suppression of HBV [J].
Qiu, Lipeng ;
Fan, Hongxia ;
Jin, Wensong ;
Zhao, Bao ;
Wang, Yanzhong ;
Ju, Ying ;
Chen, Lizhao ;
Chen, Yu ;
Duan, Zhongping ;
Meng, Songdong .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2010, 398 (04) :771-777
[53]   Micro-RNA Profiling Reveals a Role for miR-29 in Human and Murine Liver Fibrosis [J].
Roderburg, Christoph ;
Urban, Gerd-Willem ;
Bettermann, Kira ;
Vucur, Mihael ;
Zimmermann, Henning ;
Schmidt, Sabine ;
Janssen, Joern ;
Koppe, Christiane ;
Knolle, Percy ;
Castoldi, Mirco ;
Tacke, Frank ;
Trautwein, Christian ;
Luedde, Tom .
HEPATOLOGY, 2011, 53 (01) :209-218
[54]   Hepatitis B virus biology [J].
Seeger, C ;
Mason, WS .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2000, 64 (01) :51-+
[55]   Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex [J].
Sethi, Prerna ;
Lukiw, Walter J. .
NEUROSCIENCE LETTERS, 2009, 459 (02) :100-104
[56]   Viruses, microRNAs, and Host Interactions [J].
Skalsky, Rebecca L. ;
Cullen, Bryan R. .
ANNUAL REVIEW OF MICROBIOLOGY, VOL 64, 2010, 2010, 64 :123-141
[57]   Epigenetic Regulation of MicroRNA-122 by Peroxisome Proliferator Activated Receptor-gamma and Hepatitis B Virus X Protein in Hepatocellular Carcinoma Cells [J].
Song, Kyoungsub ;
Han, Chang ;
Zhang, Jinqiang ;
Lu, Dongdong ;
Dash, Srikanta ;
Feitelson, Mark ;
Lim, Kyu ;
Wu, Tong .
HEPATOLOGY, 2013, 58 (05) :1681-1692
[58]   Ectopic expression of microRNA-155 enhances innate antiviral immunity against HBV infection in human hepatoma cells [J].
Su, Chenhe ;
Hou, Zhaohua ;
Zhang, Cai ;
Tian, Zhigang ;
Zhang, Jian .
VIROLOGY JOURNAL, 2011, 8
[59]   The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice [J].
Terradillos, O ;
Billet, O ;
Renard, CA ;
Levy, R ;
Molina, T ;
Briand, P ;
Buendia, MA .
ONCOGENE, 1997, 14 (04) :395-404
[60]   Hepatitis B Virus X Protein-Induced Aberrant Epigenetic Modifications Contributing to Human Hepatocellular Carcinoma Pathogenesis [J].
Tian, Yi ;
Yang, Weibing ;
Song, Jianxun ;
Wu, Yuzhang ;
Ni, Bing .
MOLECULAR AND CELLULAR BIOLOGY, 2013, 33 (15) :2810-2816
12345678