Discovery of fluorescent cyanopyridine and deazalumazine dyes using small molecule macroarrays

被引:48
作者
Bowman, MD [1 ]
Jacobson, MM [1 ]
Blackwell, HE [1 ]
机构
[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA
关键词
D O I
10.1021/ol0602708
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Small molecule macroarrays of cyanopyridines and deazalumazines were generated in high purities via spatially addressed synthesis on planar cellulose supports. Examination of the spectral properties of the heterocycles both on and off of the planar support revealed a set of promising new fluorescent dyes that exhibit high quantum yields, low pH dependence, and high sensitivity to solvent polarity.
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页码:1645 / 1648
页数:4
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