CT imaging of pulmonary embolism in patients with COVID-19 pneumonia: a retrospective analysis

被引:26
作者
Espallargas, Irene [1 ,2 ]
Rodriguez Sevilla, Juan Jose [3 ]
Rodriguez Chiaradia, Diego Agustin [4 ,5 ,6 ,7 ]
Salar, Antonio [3 ,5 ]
Casamayor, Guillem [8 ]
Villar-Garcia, Judit [5 ,9 ]
Rodo-Pin, Anna [4 ,5 ,6 ,7 ]
Marsico, Salvatore [1 ]
Carbullanca, Santiago [1 ]
Ramal, Diego [1 ]
Alexander del Carpio, Luis [1 ]
Gayete, Angel [1 ]
Maria Maiques, Jose [1 ]
Zuccarino, Flavio [1 ,10 ]
机构
[1] Hosp del Mar, Dept Radiol, Passeig Maritim 23-25, Barcelona 08003, Spain
[2] Hosp Badalona Germans Trias & Pujol, Dept Radiol, Carretera Canyet S-N, Badalona 08916, Spain
[3] Hosp del Mar, Dept Hematol, Passeig Maritim 23-25, Barcelona 08003, Spain
[4] Hosp del Mar, Pulmonol Dept, Passeig Maritim 23-25, Barcelona 08003, Spain
[5] Inst Hosp Mar Invest Med IMIM, Dr Aiguader 88, Barcelona 08003, Spain
[6] Univ Pompeu Fabra UPF, Dr Aiguader 88, Barcelona 08003, Spain
[7] ISCIII, CIBERES, Calle Melchor Fernandez Almagro 3, Madrid 28029, Spain
[8] Hosp Badalona Germans Trias & Pujol, Dept Emergency Med, Carretera Canyet S-N, Badalona 08916, Spain
[9] Hosp del Mar, Dept Infect Dis, Passeig Maritim 23-25, Barcelona 08003, Spain
[10] Hosp St Joan de Deu, Dept Radiol, Passeig St Joan de Deu 2, Barcelona 08950, Spain
关键词
Computed tomography angiography; Pulmonary embolism; COVID-19; Fibrin fragment D; Intensive care units;
D O I
10.1007/s00330-020-07300-y
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objectives To describe imaging and laboratory findings of confirmed PE diagnosed in COVID-19 patients and to evaluate the characteristics of COVID-19 patients with clinical PE suspicion. Characteristics of patients with COVID-19 and PE suspicion who required admission to the intensive care unit (ICU) were also analysed. Methods A retrospective study from March 18, 2020, until April 11, 2020. Inclusion criteria were patients with suspected PE and positive real-time reverse-transcription polymerase chain reaction (RT-PCR) for SARS-CoV-2. Exclusion criteria were negative or inconclusive RT-PCR and other chest CT indications. CTPA features were evaluated and severity scores, presence, and localisation of PE were reported.d-dimer and IL-6 determinations, ICU admission, and previous antithrombotic treatment were registered. Results Forty-seven PE suspicions with confirmed COVID-19 underwent CTPA. Sixteen patients were diagnosed with PE with a predominant segmental distribution. Statistically significant differences were found in the highestd-dimer determination in patients with PE and ICU admission regarding elevated IL-6 values. Conclusion PE in COVID-19 patients in our series might predominantly affect segmental arteries and the right lung. Results suggest that the higher thed-dimer concentration, the greater the likelihood of PE. Both assumptions should be assessed in future studies with a larger sample size.
引用
收藏
页码:1915 / 1922
页数:8
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