Spreading and segregation of lipids in air-stable lipid microarrays

被引:11
作者
Fang, Y [1 ]
机构
[1] Corning Inc, Biochem Technol, Div Sci & Technol, Corning, NY 14831 USA
关键词
D O I
10.1021/ja058166t
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
As a result of heterogeneous spreading of distinct lipids within the same microspots of air-stable lipid microarrays, ganglioside GM1 tends to segregate and thus enrich within the center area of microspots where being predetermined by the quill pin used for array fabrication, as indicated by the binding pattern of fluorescein-cholera toxin subunit B. Copyright © 2006 American Chemical Society.
引用
收藏
页码:3158 / 3159
页数:2
相关论文
共 19 条
  • [1] Quantitative measurements of recombinant HIV surface glycoprotein 120 binding to several glycosphingolipids expressed in planar supported lipid bilayers
    Conboy, JC
    McReynolds, KD
    Gervay-Hague, J
    Saavedra, SS
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (06) : 968 - 977
  • [2] Optical biosensor provides insights for bradykinin B2 receptor signaling in A431 cells
    Fang, Y
    Li, GS
    Peng, JL
    [J]. FEBS LETTERS, 2005, 579 (28): : 6365 - 6374
  • [3] Air-stable G protein-coupled receptor microarrays and ligand binding characteristics
    Fang, Y
    Peng, JL
    Ferrie, AM
    Burkhalter, RS
    [J]. ANALYTICAL CHEMISTRY, 2006, 78 (01) : 149 - 155
  • [4] Ganglioside microarrays for toxin detection
    Fang, Y
    Frutos, AG
    Lahiri, J
    [J]. LANGMUIR, 2003, 19 (05) : 1500 - 1505
  • [5] Membrane protein microarrays
    Fang, Y
    Frutos, AG
    Lahiri, J
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (11) : 2394 - 2395
  • [6] Emerging themes in lipid rafts and caveolae
    Galbiati, F
    Razani, B
    Lisanti, MP
    [J]. CELL, 2001, 106 (04) : 403 - 411
  • [7] Imaging nanometer domains of β-adrenergic receptor complexes on the surface of cardiac myocytes
    Ianoul, A
    Grant, DD
    Rouleau, Y
    Bani-Yaghoub, M
    Johnston, LJ
    Pezacki, JP
    [J]. NATURE CHEMICAL BIOLOGY, 2005, 1 (04) : 196 - 202
  • [8] Src tyrosine kinases, G(alpha) subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin - Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases
    Li, SW
    Couet, J
    Lisanti, MP
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (46) : 29182 - 29190
  • [9] PERIODIC STRUCTURES IN LIPID MONOLAYER PHASE-TRANSITIONS
    MCCONNELL, HM
    TAMM, LK
    WEIS, RM
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-PHYSICAL SCIENCES, 1984, 81 (10): : 3249 - 3253
  • [10] Controlling molecular diffusion in self-spreading lipid bilayer using periodic array of ultra-small metallic architecture on solid surface
    Nabika, H
    Sasaki, A
    Takimoto, B
    Sawai, Y
    He, S
    Murakoshi, K
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (48) : 16786 - 16787