Radiotherapy in the management of localized primary cutaneous B-cell lymphoma

被引：7

作者：

Pashtan, Itai ^{[1
]}

Mauch, Peter M. ^{[2
,3
]}

Chen, Yu-Hui ^{[4
]}

Dorfman, David M. ^{[5
]}

Silver, Barbara ^{[2
,3
]}

Ng, Andrea K. ^{[2
,3
]}

机构：

[1] Harvard Radiat Oncol Program, Boston, MA USA

[2] Dana Farber Brigham & Womens Canc Ctr, Dept Radiat Oncol, Boston, MA USA

[3] Harvard Univ, Sch Med, Boston, MA USA

[4] Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02115 USA

[5] Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA

来源：

LEUKEMIA & LYMPHOMA | 2013年 / 54卷 / 04期

关键词：

Primary cutaneous B-cell lymphoma; prognosis; radiation; dose; local control; TREATMENT-OF-CANCER; WHO-EORTC CLASSIFICATION; EUROPEAN-ORGANIZATION; UNITED-STATES; PROPOSAL; SYSTEM;

D O I：

10.3109/10428194.2012.723707

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The optimal therapy and radiation dose for patients with localized primary cutaneous B-cell lymphoma (PCBCL) are unknown. We retrospectively identified 23 patients with localized (T1-T2) PCBCL treated with definitive radiation to doses ranging from 30 to 44 Gy (median, 36 Gy). With a median follow-up of 4.8 years, the 5-year overall survival rate was 100%, the relapse-free survival rate was 71% (95% confidence interval, 46-86%) and there were no local recurrences, suggesting that radiotherapy to a dose of 30 Gy may be sufficient for cure.

引用

页码：726 / 730

页数：5

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