Radiotherapy in the management of localized primary cutaneous B-cell lymphoma

被引：7
|
作者：
Pashtan, Itai [1 ]
Mauch, Peter M. [2 ,3 ]
Chen, Yu-Hui [4 ]
Dorfman, David M. [5 ]
Silver, Barbara [2 ,3 ]
Ng, Andrea K. [2 ,3 ]
机构：
[1] Harvard Radiat Oncol Program, Boston, MA USA
[2] Dana Farber Brigham & Womens Canc Ctr, Dept Radiat Oncol, Boston, MA USA
[3] Harvard Univ, Sch Med, Boston, MA USA
[4] Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02115 USA
[5] Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA
来源：
LEUKEMIA & LYMPHOMA | 2013年 / 54卷 / 04期
关键词：
Primary cutaneous B-cell lymphoma; prognosis; radiation; dose; local control; TREATMENT-OF-CANCER; WHO-EORTC CLASSIFICATION; EUROPEAN-ORGANIZATION; UNITED-STATES; PROPOSAL; SYSTEM;
D O I：
10.3109/10428194.2012.723707
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The optimal therapy and radiation dose for patients with localized primary cutaneous B-cell lymphoma (PCBCL) are unknown. We retrospectively identified 23 patients with localized (T1-T2) PCBCL treated with definitive radiation to doses ranging from 30 to 44 Gy (median, 36 Gy). With a median follow-up of 4.8 years, the 5-year overall survival rate was 100%, the relapse-free survival rate was 71% (95% confidence interval, 46-86%) and there were no local recurrences, suggesting that radiotherapy to a dose of 30 Gy may be sufficient for cure.
引用
收藏
页码：726 / 730
页数：5
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