Radiotherapy in the management of localized primary cutaneous B-cell lymphoma

被引：7
作者：
Pashtan, Itai [1 ]
Mauch, Peter M. [2 ,3 ]
Chen, Yu-Hui [4 ]
Dorfman, David M. [5 ]
Silver, Barbara [2 ,3 ]
Ng, Andrea K. [2 ,3 ]
机构：
[1] Harvard Radiat Oncol Program, Boston, MA USA
[2] Dana Farber Brigham & Womens Canc Ctr, Dept Radiat Oncol, Boston, MA USA
[3] Harvard Univ, Sch Med, Boston, MA USA
[4] Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02115 USA
[5] Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA
来源：
LEUKEMIA & LYMPHOMA | 2013年 / 54卷 / 04期
关键词：
Primary cutaneous B-cell lymphoma; prognosis; radiation; dose; local control; TREATMENT-OF-CANCER; WHO-EORTC CLASSIFICATION; EUROPEAN-ORGANIZATION; UNITED-STATES; PROPOSAL; SYSTEM;
D O I：
10.3109/10428194.2012.723707
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The optimal therapy and radiation dose for patients with localized primary cutaneous B-cell lymphoma (PCBCL) are unknown. We retrospectively identified 23 patients with localized (T1-T2) PCBCL treated with definitive radiation to doses ranging from 30 to 44 Gy (median, 36 Gy). With a median follow-up of 4.8 years, the 5-year overall survival rate was 100%, the relapse-free survival rate was 71% (95% confidence interval, 46-86%) and there were no local recurrences, suggesting that radiotherapy to a dose of 30 Gy may be sufficient for cure.
引用
收藏
页码：726 / 730
页数：5
相关论文
共 14 条
[1]   Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3884 cases [J].
Bradford, Porcia T. ;
Devesa, Susan S. ;
Anderson, William F. ;
Toro, Jorge R. .
BLOOD, 2009, 113 (21) :5064-5073
[2]   TOXICITY CRITERIA OF THE RADIATION-THERAPY ONCOLOGY GROUP (RTOG) AND THE EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER (EORTC) [J].
COX, JD ;
STETZ, J ;
PAJAK, TF .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1995, 31 (05) :1341-1346
[3]   Cutaneous lymphomas reported to the national cancer institute's surveillance, epidemiology, and end results program: Applying the new WHO-European organisation for research and treatment of cancer classification system [J].
Dores, GM ;
Anderson, WF ;
Devesa, SS .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (28) :7246-7248
[4]   Long-term efficacy, curative potential, and prognostic factors of radiotherapy in primary cutaneous B-CELL lymphoma [J].
Eich, HT ;
Eich, D ;
Micke, O ;
Stützer, H ;
Casper, C ;
Krieg, T ;
Müller, RP .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2003, 55 (04) :899-906
[5]   Primary cutaneous diffuse large B-cell lymphoma, leg type - Clinicopathologic features and prognostic analysis in 60 cases [J].
Grange, Florent ;
Beylot-Barry, Marie ;
Courville, Phillipe ;
Maubec, Eve ;
Bagot, Martine ;
Vergier, Beatrice ;
Souteyrand, Pierre ;
Machet, Laurent ;
Dalac, Sophie ;
Esteve, Eric ;
Templier, Isabelle ;
Delaporte, Emmanuel ;
Avril, Marie-Francoise ;
Robert, Caroline ;
Dalle, Stephane ;
Laroche, Liliane ;
Delaunay, Michele ;
Joly, Pascal ;
Wechsler, Janine ;
Petrella, Tony .
ARCHIVES OF DERMATOLOGY, 2007, 143 (09) :1144-1150
[6]   Cancer surveillance series: Non-Hodgkin's lymphoma incidence by histologic subtype in the United States from 1978 through 1995 [J].
Groves, FD ;
Linet, MS ;
Travis, LB ;
Devesa, SS .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (15) :1240-1251
[7]  
Harris N. L., 2000, Histopathology (Oxford), V36, P69
[8]   TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the Cutaneous Lymphoma Task Force of the European Organization of Research and Treatment of Cancer (EORTC) [J].
Kim, Youn H. ;
Willemze, Rein ;
Pimpinelli, Nicola ;
Whittaker, Sean ;
Olsens, Elise A. ;
Ranki, Annamari ;
Dummer, Reinhard ;
Hoppe, Richard T. .
BLOOD, 2007, 110 (02) :479-484
[9]   LOW-DOSE PALLIATIVE RADIOTHERAPY FOR CUTANEOUS B- AND T-CELL LYMPHOMAS [J].
Neelis, Karen J. ;
Schimmel, Erik C. ;
Vermeer, Maarten H. ;
Senff, Nancy J. ;
Willemze, Rein ;
Noordijk, Evert M. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 74 (01) :154-158
[10]   European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas [J].
Senff, Nancy J. ;
Noordijk, Evert M. ;
Kim, Youn H. ;
Bagot, Martine ;
Berti, Emilio ;
Cerroni, Lorenzo ;
Dummer, Reinhard ;
Duvic, Madeleine ;
Hoppe, Richard T. ;
Pimpinelli, Nicola ;
Rosen, Steven T. ;
Vermeer, Maarten H. ;
Whittaker, Sean ;
Willemze, Rein .
BLOOD, 2008, 112 (05) :1600-1609
12