Emotional arousal modulates oscillatory correlates of targeted memory reactivation during NREM, but not REM sleep

被引：66

作者：

Lehmann, Mick ^{[1
,2
,3
]}

Schreiner, Thomas ^{[3
,4
]}

Seifritz, Erich ^{[1
,3
]}

Rasch, Bjoern ^{[3
,5
]}

机构：

[1] Univ Zurich, Hosp Psychiat, Dept Psychiat Psychotherapy & Psychosomat, Zurich, Switzerland

[2] Univ Zurich, Inst Psychol, Zurich, Switzerland

[3] Univ Zurich, Zurich Ctr Interdisciplinary Sleep Res ZiS, Zurich, Switzerland

[4] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands

[5] Univ Fribourg, Dept Psychol, Fribourg, Switzerland

来源：

SCIENTIFIC REPORTS | 2016年 / 6卷

基金：

瑞士国家科学基金会;

关键词：

EYE-MOVEMENT SLEEP; SLOW OSCILLATIONS; FEAR EXTINCTION; ENHANCES MEMORY; THETA RHYTHM; CONSOLIDATION; BRAIN; EXPECTANCY; SPINDLES; RIPPLES;

D O I：

10.1038/srep39229

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Rapid eye movement (REM) sleep is considered to preferentially reprocess emotionally arousing memories. We tested this hypothesis by cueing emotional vs. neutral memories during REM and NREM sleep and wakefulness by presenting associated verbal memory cues after learning. Here we show that cueing during NREM sleep significantly improved memory for emotional pictures, while no cueing benefit was observed during REM sleep. On the oscillatory level, successful memory cueing during NREM sleep resulted in significant increases in theta and spindle oscillations with stronger responses for emotional than neutral memories. In contrast during REM sleep, solely cueing of neutral (but not emotional) memories was associated with increases in theta activity. Our results do not support a preferential role of REM sleep for emotional memories, but rather suggest that emotional arousal modulates memory replay and consolidation processes and their oscillatory correlates during NREM sleep.

引用

页数：13

共 89 条

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