Granulomatous Mastitis during Chronic Antidepressant Therapy: Is It Possible a Conservative Therapeutic Approach?

被引：22

作者：

Bellavia, Maurizio ^{[2
]}

Damiano, Giuseppe ^{[2
]}

Palumbo, Vincenzo Davide ^{[2
,3
]}

Spinelli, Gabriele ^{[2
]}

Tomasello, Giovanni ^{[1
,2
]}

Marrazzo, Antonio ^{[1
]}

Ficarella, Silvia ^{[2
]}

Bruno, Antonio ^{[2
]}

Sammartano, Antonino ^{[3
]}

Fiorentini, Tiziana ^{[3
]}

Scio, Antonio ^{[3
]}

Maione, Carolina ^{[2
]}

Lo Monte, Attilio Ignazio ^{[1
,2
,3
]}

机构：

[1] Univ Palermo, Sch Med, Dept Surg & Oncol Sci, I-90127 Palermo, Italy

[2] Univ Palermo, Sch Med, Univ Hosp P Giaccone, I-90127 Palermo, Italy

[3] Univ Palermo, PhD Doctorate Course Surg Biotechnol & Regenerat, I-90127 Palermo, Italy

来源：

JOURNAL OF BREAST CANCER | 2012年 / 15卷 / 03期

关键词：

Antidepressant therapy; Hyperprolactinemia; Idiopathic granulomatous mastitis; Selective serotonin reuptake inhibitors; INDUCED HYPERPROLACTINEMIA; DOPAMINE-D-2; RECEPTORS; BREAST-CARCINOMA; SEROTONIN; 5-HT2A; MANAGEMENT;

D O I：

10.4048/jbc.2012.15.3.371

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Granulomatous mastitis is a rare benign inflammatory disease of the breast with multiple etiologies such as tuberculosis, sarcoidosis, foreign body reaction, and mycotic and parasitic infections. In contrast, idiopathic granulomatous mastitis (IGM) is characterized by the presence of chronic granulomatous lobulitis in the absence of an obvious etiology. Clinically and radiologically it may mimic breast carcinoma and so awareness of surgeons, pathologists, and radiologists is essential to avoid unnecessary mastectomies. Cases of IGM are reported during antidepressant therapy in patients also showing high levels of prolactinemia. In these cases, we believe that surgical excision must be avoided being replaced with a conservative management of the pathological condition based on a corticosteroid treatment.

引用

页码：371 / 372

页数：2