共 12 条
[1]
Understanding multicellular function and disease with human tissue-specific networks
[J].
Greene, Casey S.
;
Krishnan, Arjun
;
Wong, Aaron K.
;
Ricciotti, Emanuela
;
Zelaya, Rene A.
;
Himmelstein, Daniel S.
;
Zhang, Ran
;
Hartmann, Boris M.
;
Zaslavsky, Elena
;
Sealfon, Stuart C.
;
Chasman, Daniel I.
;
FitzGerald, Garret A.
;
Dolinski, Kara
;
Grosser, Tilo
;
Troyanskaya, Olga G.
.
NATURE GENETICS,
2015, 47 (06)
:569-576

Greene, Casey S.
论文数: 0 引用数: 0
h-index: 0
机构:
Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA
Dartmouth Hitchcock Norris Cotton Canc Ctr, Lebanon, NH USA
Dartmouth Coll, Inst Quantitat Biomed Sci, Hanover, NH 03755 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Krishnan, Arjun
论文数: 0 引用数: 0
h-index: 0
机构:
Princeton Univ, Lewis Sigler Inst Integrat Genom, Princeton, NJ 08544 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Wong, Aaron K.
论文数: 0 引用数: 0
h-index: 0
机构:
Princeton Univ, Dept Comp Sci, Princeton, NJ 08544 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Ricciotti, Emanuela
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Penn, Perelman Sch Med, Dept Syst Pharmacol & Translat Therapeut, Philadelphia, PA 19104 USA
Univ Penn, Perelman Sch Med, Inst Translat Med & Therapeut, Philadelphia, PA 19104 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Zelaya, Rene A.
论文数: 0 引用数: 0
h-index: 0
机构:
Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Himmelstein, Daniel S.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Biol & Med Informat, San Francisco, CA 94143 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Zhang, Ran
论文数: 0 引用数: 0
h-index: 0
机构:
Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Hartmann, Boris M.
论文数: 0 引用数: 0
h-index: 0
机构:
Icahn Sch Med Mt Sinai, Dept Neurol, New York, NY 10029 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Zaslavsky, Elena
论文数: 0 引用数: 0
h-index: 0
机构:
Icahn Sch Med Mt Sinai, Dept Neurol, New York, NY 10029 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Sealfon, Stuart C.
论文数: 0 引用数: 0
h-index: 0
机构:
Icahn Sch Med Mt Sinai, Dept Neurol, New York, NY 10029 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Chasman, Daniel I.
论文数: 0 引用数: 0
h-index: 0
机构:
Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Boston, MA USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

FitzGerald, Garret A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Penn, Perelman Sch Med, Dept Syst Pharmacol & Translat Therapeut, Philadelphia, PA 19104 USA
Univ Penn, Perelman Sch Med, Inst Translat Med & Therapeut, Philadelphia, PA 19104 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Dolinski, Kara
论文数: 0 引用数: 0
h-index: 0
机构:
Princeton Univ, Lewis Sigler Inst Integrat Genom, Princeton, NJ 08544 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Grosser, Tilo
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Penn, Perelman Sch Med, Dept Syst Pharmacol & Translat Therapeut, Philadelphia, PA 19104 USA
Univ Penn, Perelman Sch Med, Inst Translat Med & Therapeut, Philadelphia, PA 19104 USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA

Troyanskaya, Olga G.
论文数: 0 引用数: 0
h-index: 0
机构:
Princeton Univ, Lewis Sigler Inst Integrat Genom, Princeton, NJ 08544 USA
Princeton Univ, Dept Comp Sci, Princeton, NJ 08544 USA
Simons Fdn, Simons Ctr Data Anal, New York, NY USA Geisel Sch Med Dartmouth, Dept Genet, Hanover, NH USA
[2]
DNA Methylation on N6-Adenine in C-elegans
[J].
Greer, Eric Lieberman
;
Blanco, Mario Andres
;
Gu, Lei
;
Sendinc, Erdem
;
Liu, Jianzhao
;
Aristizabal-Corrales, David
;
Hsu, Chih-Hung
;
Aravind, L.
;
He, Chuan
;
Shi, Yang
.
CELL,
2015, 161 (04)
:868-878

Greer, Eric Lieberman
论文数: 0 引用数: 0
h-index: 0
机构:
Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA

Blanco, Mario Andres
论文数: 0 引用数: 0
h-index: 0
机构:
Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA

Gu, Lei
论文数: 0 引用数: 0
h-index: 0
机构:
Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA

论文数: 引用数:
h-index:
机构:

Liu, Jianzhao
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Howard Hughes Med Inst, Dept Chem, Chicago, IL 60637 USA
Univ Chicago, Howard Hughes Med Inst, Inst Biophys Dynam, Chicago, IL 60637 USA Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA

Aristizabal-Corrales, David
论文数: 0 引用数: 0
h-index: 0
机构:
Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA

Hsu, Chih-Hung
论文数: 0 引用数: 0
h-index: 0
机构:
Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA

Aravind, L.
论文数: 0 引用数: 0
h-index: 0
机构:
Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20894 USA Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA

He, Chuan
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Howard Hughes Med Inst, Dept Chem, Chicago, IL 60637 USA
Univ Chicago, Howard Hughes Med Inst, Inst Biophys Dynam, Chicago, IL 60637 USA Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA

Shi, Yang
论文数: 0 引用数: 0
h-index: 0
机构:
Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
[3]
Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification
[J].
Iyer, Lakshminarayan M.
;
Zhang, Dapeng
;
Aravind, L.
.
BIOESSAYS,
2016, 38 (01)
:27-40

Iyer, Lakshminarayan M.
论文数: 0 引用数: 0
h-index: 0
机构:
NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bldg 10, Bethesda, MD 20892 USA NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bldg 10, Bethesda, MD 20892 USA

Zhang, Dapeng
论文数: 0 引用数: 0
h-index: 0
机构:
NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bldg 10, Bethesda, MD 20892 USA NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bldg 10, Bethesda, MD 20892 USA

Aravind, L.
论文数: 0 引用数: 0
h-index: 0
机构:
NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bldg 10, Bethesda, MD 20892 USA NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bldg 10, Bethesda, MD 20892 USA
[4]
Natural History of Eukaryotic DNA Methylation Systems
[J].
Iyer, Lakshminarayan M.
;
Abhiman, Saraswathi
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Aravind, L.
.
MODIFICATIONS OF NUCLEAR DNA AND ITS REGULATORY PROTEINS,
2011, 101
:25-104

Iyer, Lakshminarayan M.
论文数: 0 引用数: 0
h-index: 0
机构:
NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20892 USA NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20892 USA

Abhiman, Saraswathi
论文数: 0 引用数: 0
h-index: 0
机构:
NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20892 USA NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20892 USA

Aravind, L.
论文数: 0 引用数: 0
h-index: 0
机构:
NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20892 USA NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20892 USA
[5]
Spliceosomal snRNA modifications and their function
[J].
Karijolich, John
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Yu, Yi-Tao
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RNA BIOLOGY,
2010, 7 (02)
:192-204

Karijolich, John
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Rochester, Med Ctr, Dept Biochem & Biophys, Rochester, NY 14642 USA Univ Rochester, Med Ctr, Dept Biochem & Biophys, Rochester, NY 14642 USA

Yu, Yi-Tao
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Rochester, Med Ctr, Dept Biochem & Biophys, Rochester, NY 14642 USA Univ Rochester, Med Ctr, Dept Biochem & Biophys, Rochester, NY 14642 USA
[6]
An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing
[J].
Kweon, Soo-Mi
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Chen, Yibu
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Moon, Eugene
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Kvederaviciute, Kotryna
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Klimasauskas, Saulius
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Feldman, Douglas E.
.
MOLECULAR CELL,
2019, 74 (06)
:1138-+

Kweon, Soo-Mi
论文数: 0 引用数: 0
h-index: 0
机构:
USC, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA USC, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA

Chen, Yibu
论文数: 0 引用数: 0
h-index: 0
机构:
USC, Keck Sch Med, Dept Hlth Sci Libs, Bioinformat Serv, Los Angeles, CA 90033 USA USC, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA

Moon, Eugene
论文数: 0 引用数: 0
h-index: 0
机构:
USC, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA USC, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA

Kvederaviciute, Kotryna
论文数: 0 引用数: 0
h-index: 0
机构:
Vilnius Univ, Life Sci Ctr, Inst Biotechnol, LT-10257 Vilnius, Lithuania USC, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA

Klimasauskas, Saulius
论文数: 0 引用数: 0
h-index: 0
机构:
Vilnius Univ, Life Sci Ctr, Inst Biotechnol, LT-10257 Vilnius, Lithuania USC, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA

Feldman, Douglas E.
论文数: 0 引用数: 0
h-index: 0
机构:
USC, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA USC, Keck Sch Med, Dept Pathol, Los Angeles, CA 90033 USA
[7]
Mechanisms and Regulation of Alternative Pre-mRNA Splicing
[J].
Lee, Yeon
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Rio, Donald C.
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ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84,
2015, 84
:291-323

Lee, Yeon
论文数: 0 引用数: 0
h-index: 0
机构: Univ Calif Berkeley, Ctr RNA Syst Biol, Berkeley, CA 94720 USA

Rio, Donald C.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif Berkeley, Ctr RNA Syst Biol, Berkeley, CA 94720 USA Univ Calif Berkeley, Ctr RNA Syst Biol, Berkeley, CA 94720 USA
[8]
N6-methyldeoxyadenine is a transgenerational epigenetic signal for mitochondrial stress adaptation
[J].
Ma, Chengchuan
;
Niu, Rong
;
Huang, Tianxiao
;
Shao, Li-Wa
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Peng, Yong
;
Ding, Wanqiu
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Wang, Ye
;
Jia, Guifang
;
He, Chuan
;
Li, Chuan-Yun
;
He, Aibin
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Liu, Ying
.
NATURE CELL BIOLOGY,
2019, 21 (03)
:319-+

Ma, Chengchuan
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China
Peking Univ, Acad Adv Interdisciplinary Studies, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

Niu, Rong
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

Huang, Tianxiao
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

Shao, Li-Wa
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China
Peking Univ, Acad Adv Interdisciplinary Studies, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

Peng, Yong
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China
Peking Univ, Acad Adv Interdisciplinary Studies, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

Ding, Wanqiu
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

Wang, Ye
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Coll Chem & Mol Engn, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci,Minist Educ,Synthet & Fu, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

Jia, Guifang
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Coll Chem & Mol Engn, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci,Minist Educ,Synthet & Fu, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

He, Chuan
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Coll Chem & Mol Engn, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci,Minist Educ,Synthet & Fu, Beijing, Peoples R China
Univ Chicago, Dept Chem, Chicago, IL 60637 USA
Univ Chicago, Inst Biophys Dynam, Chicago, IL 60637 USA
Univ Chicago, Howard Hughes Med Inst, Chicago, IL 60637 USA Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

Li, Chuan-Yun
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

He, Aibin
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China

Liu, Ying
论文数: 0 引用数: 0
h-index: 0
机构:
Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China Peking Univ, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med, State Key Lab Membrane Biol, Beijing, Peoples R China
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CRISPR/Cas9-mediated integration enables TAG-eCLIP of endogenously tagged RNA binding proteins
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Van Nostrand, Eric L.
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Gelboin-Burkhart, Chelsea
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Wang, Ruth
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Pratt, Gabriel A.
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Blue, Steven M.
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Yeo, Gene W.
.
METHODS,
2017, 118
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Van Nostrand, Eric L.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA
Univ Calif San Diego, Stem Cell Program, La Jolla, CA 92093 USA
Univ Calif San Diego, Inst Genom Med, La Jolla, CA 92093 USA Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA

Gelboin-Burkhart, Chelsea
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA
Univ Calif San Diego, Stem Cell Program, La Jolla, CA 92093 USA
Univ Calif San Diego, Inst Genom Med, La Jolla, CA 92093 USA Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA

Wang, Ruth
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA
Univ Calif San Diego, Stem Cell Program, La Jolla, CA 92093 USA
Univ Calif San Diego, Inst Genom Med, La Jolla, CA 92093 USA Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA

Pratt, Gabriel A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA
Univ Calif San Diego, Stem Cell Program, La Jolla, CA 92093 USA
Univ Calif San Diego, Inst Genom Med, La Jolla, CA 92093 USA
Univ Calif San Diego, Bioinformat & Syst Biol Grad Program, La Jolla, CA 92093 USA Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA

Blue, Steven M.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA
Univ Calif San Diego, Stem Cell Program, La Jolla, CA 92093 USA
Univ Calif San Diego, Inst Genom Med, La Jolla, CA 92093 USA Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA

Yeo, Gene W.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA
Univ Calif San Diego, Stem Cell Program, La Jolla, CA 92093 USA
Univ Calif San Diego, Inst Genom Med, La Jolla, CA 92093 USA
Univ Calif San Diego, Bioinformat & Syst Biol Grad Program, La Jolla, CA 92093 USA
Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Physiol, Singapore, Singapore
ASTAR, Mol Engn Lab, Singapore, Singapore Univ Calif San Diego, Dept Cellular & Mol Med, La Jolla, CA 92093 USA