Acquisition of the cat scratch disease agent Bartonella henselae by cat fleas (Siphonaptera: Pulicidae)

被引：141

作者：

Higgins, JA

Radulovic, S

Jaworski, DC

Azad, AF

机构：

[1] Dept. of Microbiology and Immunology, University of Maryland, Medical School, Baltimore

来源：

JOURNAL OF MEDICAL ENTOMOLOGY | 1996年 / 33卷 / 03期

关键词：

Bartonella henselae; Ctenocephalides felis; cat fleas; cat scratch disease;

D O I：

10.1093/jmedent/33.3.490

中图分类号：

Q96 [昆虫学];

学科分类号：

摘要：

We assayed the ability of cat fleas to become infected with Bartonella henselae, using an artificial feeding device. Fleas fed a concentration of 1 x 10(5) cfu/ml in blood were examined using immunofluorescent antibody assay and polymerase chain reaction. Bacteria were present in the gut at 3 h, and persisted up to 9 d after infection. Qualitatively, the density of B. henselae was greater in the flea gut at 9 d, indicating that replication was occurring in the gut. B. henselae also was detected in the feces of infected fleas 9 d after infection, and produced viable colonies upon inoculation onto heart infusion agar/rabbit blood plates. Our results indicate that fleas can maintain infection with B. henselae, and may play a role in the transmission of this bacterium from infected cats to humans.

引用

页码：490 / 495

页数：6

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